LOINC
Version 2.67

73823-7Cocaine+Benzoylecgonine [Presence] in Serum, Plasma or Blood by Screen methodActive

Part Descriptions

LP36028-6   Cocaine+Benzoylecgonine
Cocaine is an alkaloid of Erythroxylon coca that is grown in the northern South American Andes, India, Africa and Java. It is used medicinally as a local anesthetic and vasoconstrictor in nasal surgery and to dilate pupils. Because cocaine is a powerful central nervous system stimulant it is among the most abused drugs. Cocaine abuse can lead to sudden death due to cardiotoxicity or the sequential development of hyperthermia, agitated delirium and respiratory arrest. Cocaine is metabolized in the liver to inactive benzoylecgonine (BZE). BZE is pharmacologically inactive and has a longer half-life than its parent drug cocaine. It is the substance most tested for when investigating suspected cocaine abuse. Cocaethylene (CE) is produced in the liver in the presence of ethanol and has been shown to have similar stimulatory effects as cocaine in animal studies.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition) Cocaethylene is toxic to the myocardium. [PMID: 8761012] Source: Regenstrief LOINC

LP36028-6   Cocaine+Benzoylecgonine
Benzoylecgonine is the major metabolite of cocaine. It is a biological metabolite with a stable structure that resists hydrolysis, both in the body and in the environment. Benzoylecgonine remains in the body for a few days and is commonly used as a marker in drug tests. [PMCID: 1929267] [PMID: 27224254] Source: Regenstrief LOINC

Fully-Specified Name

Component
Cocaine+Benzoylecgonine
Property
PrThr
Time
Pt
System
Ser/Plas/Bld
Scale
Ord
Method
Screen

Additional Names

Short Name
Cocaine+BZE SerPlBld Ql Scn
Display Name
Cocaine+Benzoylecgonine Screen Ql (S/P/Bld)

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.44
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Groups

LG50145-8 Cocaine+Benzoylecgonine|ANYProp|ANYTm|ANYSys|ANYMeth

Language Variants Get Info

zh-CNChinese (CHINA)
可卡因+苯甲酰芽子碱:存在情况或阈值:时间点:血清/血浆/全血:序数型:毒理学筛查试验
nl-NLDutch (NETHERLANDS)
cocaïne + benzoylecgonine:aanwezigheid:moment:serum of plasma of bloed:ordinaal:screening
fr-BEFrench (BELGIUM)
Cocaïne+Benzoylecgonine:PrThr:Temps ponctuel:Sérum/Plasma/Sang:Ordinal:Dépistage
fr-CAFrench (CANADA)
Cocaïne+Benzoylecgonine:Présence-Seuil:Temps ponctuel:Sérum/Plasma/Sang:Ordinal:Dépistage
fr-FRFrench (FRANCE)
Cocaïne+benzoylecgonine:Présence/Seuil:Ponctuel:Sérum/Plasma/Sang:Qualitatif:Dépistage
it-ITItalian (ITALY)
Cocaina+Benzoilecgonina:PrThr:Pt:Siero/Plasma/Sangue:Ord:Screening
pt-BRPortuguese (BRAZIL)
Cocaína+Benzoilecgonina:Limiar:Pt:Soro/Plas/Sg:Ord:Triagem
ru-RURussian (RUSSIAN FEDERATION)
Кокаин+Бензоилэкгонин:PrThr:ТчкВрм:Сыв/Плаз/Кр:Пор:Скрининг
es-ESSpanish (SPAIN)
Cocaina+Benzoilecgonina:PrThr:Punto temporal:Suero, Plasma o Sangre:Ord:Cribado toxicológico
tr-TRTurkish (TURKEY)
Kokain+Benzoilekgonin:MevcEşik:Zmlı:Ser/Plaz/Kan:Srl:Tarama

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=73823-7