Version 2.73

74122-3Ubiquitin Ag [Presence] in Tissue by Immune stainActive

Term Description

Detects the presence of intracellular ubiquitinated filamentous inclusions in the periphery of senile plaques and neurofibrillary tangles in Alzheimer disease and lewy bodies in Parkinsion disease.
Source: Regenstrief LOINC

Part Description

LP173629-9   Ubiquitin
Ubiquitin is a small (8.5 kDa) regulatory protein that has been found in almost all tissues (ubiquitously) of eukaryotic organisms. There are four genes in the human genome that produce ubiquitin; UBB, UBC, UBA52 and RPS27A. Immunohistochemistry using antibodies to ubiquitin can identify abnormal accumulations of this protein inside cells, indicating a disease process. These protein accumulations are referred to as inclusion bodies (which is a general term for any microscopically visible collection of abnormal material in a cell). Examples include neurofibrillary tangles in Alzheimer disease, lewy body in Parkinson disease, pick bodies in Pick's disease, and inclusions in motor neuron disease and Huntington disease. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia

Fully-Specified Name

Ubiquitin Ag
Immune stain

Additional Names

Short Name
Ubiquitin Ag Tiss Ql ImStn
Display Name
Ubiquitin Ag Immune stain Ql (Tiss)
Consumer Name Alpha
Ubiquitin antigen, Tissue

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.46
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation

Language Variants Get Info

zh-CNChinese (China)
泛素 抗原:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法
nl-NLDutch (Netherlands)
ubiquitine Ag:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring
fr-FRFrench (France)
Ubiquitine antigène:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Coloration immune
it-ITItalian (Italy)
Ubiquitina , Ag:PrThr:Pt:Tessuto:Ord:Colorazione immunologica
pt-BRPortuguese (Brazil)
Ubiquitina Ag::Pt:Tecido:Ord:Imunocoloração
ru-RURussian (Russian Federation)
Убихитин Аг:PrThr:ТчкВрм:Тк:Пор:Иммуногистохимическая окраска
es-MXSpanish (Mexico)
Ubiquitin Ag:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Mancha inmune
es-ESSpanish (Spain)
Ubiquitina Antígeno:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
tr-TRTurkish (Turkey)
Ubikitin Ag:MevcEşik:Zmlı:Doku:Srl:İmmün boyama

LOINC FHIR® API Example - CodeSystem Request Get Info