LOINC
Version 2.67

74678-4Carboxy tetrahydrocannabinol [Presence] in Saliva (oral fluid) by Confirmatory methodActive

Part Descriptions

LP14468-0   Carboxy tetrahydrocannabinol
Carboxy THC is the major metabolite of cannabinoid found in urine, but is not related to source, time of exposure, amount, or impairment. Carboxy THC may be found in urine for 7-10 days following light or moderate use and as long as 4-6 weeks following heavy use. THC metabolites are stored rapidly in body fat following use and are released slowly over time. Source: Regenstrief Institute

LP14468-0   Carboxy tetrahydrocannabinol
11-nor-9-carboxy-delta-9-THC is the major metabolite (carboxy THC) in urine but is not related to source, time of exposure, amount, or impairment. Rapid storage of THC metabolites in body fat occurs after use. These substances are then released from storage sites slowly over time. A marijuana cigarette is made from the dried leaves of the plant, Cannabis sativa. The immediate effects of smoking marijuana include a faster heartbeat and pulse rate, bloodshot eyes, and a dry mouth and throat. The drug can impair or reduce short-term memory, alter sense of time, and reduce the ability to do things which require concentration, swift reactions and coordination, such as driving and operating machinery. Information from LOINC partner 1.com. Source: Regenstrief Institute

LP7565-7   Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. [PMID: 17268583] Source: Regenstrief LOINC

LP262420-5   Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. [PMID: 17268583] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, Tetrahydrocannabinol (Wikipedia)

Fully-Specified Name

Component
Carboxy tetrahydrocannabinol
Property
PrThr
Time
Pt
System
Saliva
Scale
Ord
Method
Confirm

Additional Names

Short Name
CarboxyTHC Sal Ql Cfm
Display Name
Carboxy tetrahydrocannabinol Confirm Ql (Sal)

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.48
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Groups

LG37596-0 Carboxy tetrahydrocannabinol|ANYProp|ANYTm|ANYSys|ANYMeth

Language Variants Get Info

zh-CNChinese (CHINA)
羧基四氢大麻酚:存在情况或阈值:时间点:唾液:序数型:毒理学确认试验
nl-NLDutch (NETHERLANDS)
carboxytetrahydrocannabinol:aanwezigheid:moment:speeksel:ordinaal:bevestiging
et-EEEstonian (ESTONIA)
Karboksütetrahüdrokannabinool:PrThr:Pt:Sal:Ord:Kinnitav
fr-BEFrench (BELGIUM)
Carboxy tétrahydrocannabinol:PrThr:Temps ponctuel:Salivaire:Ordinal:Confirmé
fr-CAFrench (CANADA)
Carboxy tétrahydrocannabinol:Présence-Seuil:Temps ponctuel:Salivaire:Ordinal:Confirmé
fr-FRFrench (FRANCE)
11-nor-tétrahydrocannabinol carboxylique:Présence/Seuil:Ponctuel:Salive:Qualitatif:Confirmation
it-ITItalian (ITALY)
Carbossi tetraidrocannabinolo:PrThr:Pt:Saliva:Ord:Conferma
pt-BRPortuguese (BRAZIL)
Carboxi tetrahidrocannabinol:Limiar:Pt:Saliva:Ord:Confirmatório
ru-RURussian (RUSSIAN FEDERATION)
Карбокситетрагидроканнабиол:PrThr:ТчкВрм:Слюна:Пор:Подтверждать
es-ESSpanish (SPAIN)
Carboxi tetrahidrocannabinol:PrThr:Punto temporal:Saliva:Ord:Confirmatorio
tr-TRTurkish (TURKEY)
Karboksi tetrahidrokannabinol:MevcEşik:Zmlı:Tükürük:Srl:Onay

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74678-4