LOINC
Version 2.69

75378-0Hepatitis B virus core Ab [Presence] in Serum, Plasma or Blood by Rapid immunoassayActive

Term Description

Hepatitis B core Ab (HBcAb) rapid tests are available in test strip and cassette formats from manufacturers in various countries including the US, Singapore, and China. Hepatitis B core Ab (HBcAb) rapid tests are useful screening tests for acute hepatitis B because HBcAb is the first antibody to appear in acute hepatitis B infections. During the window period of acute hepatitis B, (after HBsAg disappears and before HBsAb appears), HBcAb is sometimes the only serologic marker detected. High levels of HBcAb persist long term, making these rapid tests useful for detecting past history of hepatitis B infection. This term was based on, but not limited in use to, the iCare One Step HBcAb test kit which is a is a competitive colloidal gold enhanced immunoassay for the detection of anti-HBc antigen(HBcAb) in human serum or plasma. Testing can be done in approximately 15 minutes.
Source: Regenstrief LOINC

Part Descriptions

LP14414-4   Hepatitis B virus core
The hepatitis B surface antigen (HBsAg) is most frequently used to screen for the presence of this infection. It is the first detectable viral antigen to appear during infection. However, early in an infection, this antigen may not be present and it may be undetectable later in the infection as it is being cleared by the host. The infectious virion contains an inner "core particle" enclosing viral genome. The icosahedral core particle is made of 180 or 240 copies of core protein, alternatively known as hepatitis B core antigen, or HBcAg. During this 'window' in which the host remains infected but is successfully clearing the virus, IgM antibodies to the hepatitis B core antigen (anti-HBc IgM) may be the only serological evidence of disease. Therefore most hepatitis B diagnostic panels contain HBsAg and total anti-HBc(both IgM and IgG). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Hepatitis B Virus

LP38323-9   Hepatitis B virus core Ab
Hepatitis B core antibody (anti-HBc) appears at the onset of symptoms in acute hepatitis B and persists for life. Presence of anti-HBc indicates previous or ongoing infection with
hepatitis B virus in an undefined time frame. Source: Regenstrief LOINC, Interpretation of Hepatitis B Serologic Test Results

Fully-Specified Name

Component
Hepatitis B virus core Ab
Property
PrThr
Time
Pt
System
Ser/Plas/Bld
Scale
Ord
Method
IA.rapid

Additional Names

Short Name
HBV core Ab SerPlBld Ql IA.rapid
Display Name
HBV core Ab IA.rapid Ql (S/P/Bld)
Consumer Name Alpha
Hepatitis B virus (HBV) Core antibody, Blood

Example Answer List LL2021-5

Source: Gen-Probe

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
Invalid LA15841-2

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.50
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Observation

Member of these Groups

LG32752-4 Hepatitis B virus

Language Variants Get Info

zh-CNChinese (China)
乙型肝炎病毒核心 抗体:存在情况或阈值:时间点:血清/血浆/全血:序数型:免疫测定法.快速
nl-NLDutch (Netherlands)
Hepatitis B-virus core As:aanwezigheid:moment:serum of plasma of bloed:ordinaal:immunoassay.sneltest
fr-BEFrench (Belgium)
Noyau du virus de l'hépatite B Ac:PrThr:Temps ponctuel:Sérum/Plasma/Sang:Ordinal:IA.rapid
fr-CAFrench (Canada)
Noyau du virus de l'hépatite B , Ac:Présence-Seuil:Temps ponctuel:Sérum/Plasma/Sang:Ordinal:IA.rapide
fr-FRFrench (France)
Hépatite B virus core Ac:Présence/Seuil:Ponctuel:Sérum/Plasma/Sang:Qualitatif:Immunoanalyse rapide
it-ITItalian (Italy)
Epatite B virus, core , Ab:PrThr:Pt:Siero/Plasma/Sangue:Ord:IA.rapido
ru-RURussian (Russian Federation)
Гепатита В вируса сердцевина Ат:PrThr:ТчкВрм:Сыв/Плаз/Кр:Пор:IA.rapid
es-ESSpanish (Spain)
Antígeno del core virus Hepatitis B Anticuerpos:PrThr:Punto temporal:Suero, Plasma o Sangre:Ord:IA.rapid
tr-TRTurkish (Turkey)
Hepatit B virüsü core Ab:MevcEşik:Zmlı:Ser/Plaz/Kan:Srl:İA.hızlı

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=75378-0