LOINC
Version 2.72

75683-3Deprecated Carbapenem resistance blaKPC gene [Presence] by Nucleic acid capture and probe detection in Positive blood cultureDeprecated

Status Information

Status
Deprecated
Reason
Duplicate
Comment
Recommend using the term with System Isolate/Specimen and Method Molgen that aligns with the new LOINC model for molecular resistance testing that was approved by Laboratory LOINC Committee in June 2018
Map-To Long Common Name Mapping Guidance
49617-4 Carbapenem resistance blaKPC gene [Presence] by Molecular method

Part Descriptions

LP64707-0   Bacterial carbapenem resistance blaKPC gene
Non-susceptibility to carbapenems in gram-negative bacilli by means of the enzyme KPC (Klebsiella pneumoniae carbapenemase) is becoming more common. The gene beta-lactamase KPC (bla(KPC)) encodes KPC enzyme production, which in turn hydrolyzes and inactivates carbapenem antibiotics. KPC enzymes are a class A beta lactamases with several variants (KPC-2, KPC-3, etc) known. Various methods are used to detect specific portions of genes encoding KPC production. Carbapenemases can also be detected by other methods, including the modified Hodge test to detect carbapenemase production in isolates and minimum inhibitory concentration (MIC) to determine level of resistance. Source: Regenstrief LOINC

LP183540-6   Probe.mag capture
Nucleic acid is first concentrated and purified using a bead-based method, followed by a oligonucleotide probe detection of sequence of interest with signal enhancement. Source: Regenstrief LOINC

Fully-Specified Name

Component
Bacterial carbapenem resistance blaKPC gene
Property
PrThr
Time
Pt
System
Bld.pos growth
Scale
Ord
Method
Probe.mag capture

Additional Names

Short Name
Deprecated blaKPC Bld Pos Ql Prb Mag
Display Name
Carbapenem resistance blaKPC gene Nucleic acid capture and probe detection Ql (Pos bld culture)
Consumer Name Alpha
Carbapenem resistance blaKPC gene, Infected blood

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.50
Last Updated
Version 2.65
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Corrected Component from "Bacterial carbapenemase resistance" to "Bacterial carbapenem resistance" (because the bacteria are resistant to carbapenem antibiotics by virtue of producing carbapenemase) and removed parentheses around and within the gene name according to recommended nomenclature [PMID: 25249841]
Order vs. Observation
Observation

Language Variants Get Info

zh-CNChinese (China)
细菌碳青霉烯类耐药 blaKPC 基因:存在情况或阈值:时间点:血液.生长阳性:序数型:探针.磁捕获
fr-FRFrench (France)
Résistance bactérienne aux carbapénèmases blaKPC gène:Présence/Seuil:Ponctuel:Hémoculture positive:Qualitatif:Sonde de capture magnétique
it-ITItalian (Italy)
Resistenza batterica ai carbapenemici, gene blaKPC:PrThr:Pt:Emocolture positive:Ord:Sonda.cattura mag
es-MXSpanish (Mexico)
Gen blaKPC de resistencia a carbapenémicos bacterianos:Presencia o umbral:Punto temporal:Hemocultivo positivo:Ordinal:Hibridación de captura magnética
es-ESSpanish (Spain)
Gen bla(KPC):PrThr:Punto temporal:Sangre crecimiento positivo:Ord:Hibridación por capturas magnéticas

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=75683-3