LOINC
Version 2.73

76494-4Tacrolimus [Moles/volume] in Blood by ImmunoassayActive

Term Description

This term was created for but not limited in use to, the cobas Tacrolimus test kit which uses a competition principle immunoassay.
Source: Regenstrief LOINC

Part Descriptions

LP15182-6   Tacrolimus
Tacrolimus (also known as FK-506 or Prograf) is a macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis. It has strong immunosuppressive properties and is commonly used to prevent allograft rejection in transplant recipients. One of its modes of action is to prevent T-lymphocyte activation. Source: National Library of Medicine, MeSH 2006

LP15182-6   Tacrolimus
Tacrolimus (also called FK-506 or fujimycin, Prograf, Advagraf, or Protopic) is amacrolide lactone, calcineurin inhibitor immunosuppresent used mainly after allogeneic organ transplant to lower the risk of organ rejection. It possesses strong immunosuppressive activity by preventing the activation by of T-lymphocytes in response to antigenic or mitogenic stimulation. Tacrolimus is also used in a topical preparation in the treatment of atopic dermatitis (eczema), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, TH2-mediated diseases such as Kimura's disease, and the skin condition vitiligo. There are potentially severe side effects from doses that are either too low or too high; inadequate tacrolimus concentrations may result in rejection of the transplanted organ, while high levels may lead to severe adverse effects includin nephrotoxicity, neurotoxicity, gastrointestinal disturbances, diabetogenesis, hypertension and malignant complications. [Wikipedia:Tacrolimus] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Tacrolimus

Fully-Specified Name

Component
Tacrolimus
Property
SCnc
Time
Pt
System
Bld
Scale
Qn
Method
IA

Additional Names

Short Name
Tacrolimus Bld IA-sCnc
Display Name
Tacrolimus IA (Bld) [Moles/Vol]
Consumer Name Alpha
Tacrolimus, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.56
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups

LG47896-2 Tacrolimus|Pt|Bld|IA

Language Variants Get Info

zh-CNChinese (China)
他克莫司:物质的量浓度:时间点:全血:定量型:免疫测定法
nl-NLDutch (Netherlands)
tacrolimus:mol/volume:moment:bloed:kwantitatief:immunoassay
et-EEEstonian (Estonia)
Takroliimus:SCnc:Pt:B:Qn:IA
fr-BEFrench (Belgium)
Tacrolimus:Concentration de substance:Temps ponctuel:Sang:Quantitatif:IA
fr-CAFrench (Canada)
Tacrolimus:Concentration de substance:Temps ponctuel:Sang:Quantitatif:IA
fr-FRFrench (France)
Tacrolimus:Moles/Volume:Ponctuel:Sang:Numérique:Immunoanalyse
de-DEGerman (Germany)
Tacrolimus:Stoffmengenkonzentration:Zeitpunkt:Blut:Quantitativ:Immunoassay
el-GRGreek (Greece)
Τακρόλιμους:Συγκέντρωση ουσίας:Χρονική στιγμή:Αίμα:Ποσοτική:IA
it-ITItalian (Italy)
Tacrolimus:SCnc:Pt:Sangue:Qn:IA
ru-RURussian (Russian Federation)
Такролимус:МолКонц:ТчкВрм:Кр:Колич:IA
es-MXSpanish (Mexico)
Tacrolimus:Concentración de sustancias:Punto temporal:Sangre:Cuantitativo:Inmunoensayo
es-ESSpanish (Spain)
Tacrolimus:Concentración de sustancia:Punto temporal:Sangre:Qn:IA
tr-TRTurkish (Turkey)
Takrolimus:SubKons:Zmlı:Kan:Kant:İA

Example Units

Unit Source
nmol/L Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=76494-4