LOINC
Version 2.67

76545-3Breast cancer 10-year risk of distant recurrence classification [Interpretation] Qualitative by ProsignaActive

Term Description

The risk classification is an ordinal risk category (low, intermediate, high) that indicates a patient's risk of recurrence of breast cancer at 10 years. The classification is based on the 10-year risk of distant recurrence score and lymph node status. Low risk is associated with a 3% chance (confidence interval 2-6%), intermediate risk is associated with a 10% chance (confidence interval 7-14%), and high risk with a 16% chance (confidence interval 11-22%) of distant breast cancer recurrence at 10 years, respectively. [PMID: 24347518] This term was created for the Prosigna™ Breast Cancer Prognostic Gene Signature assay, which is intended for use in postmenopausal women with node-negative (Stage I or II) or node-positive (Stage II), hormone receptor-positive (HR+) breast cancer who have undergone surgery and are to be treated with adjuvant endocrine therapy alone.
Source: Regenstrief LOINC

Fully-Specified Name

Component
Breast cancer 10Y risk of distant recurrence classification
Property
Imp
Time
Pt
System
^Patient
Scale
Ord
Method
Prosigna

Additional Names

Short Name
Brst ca 10Y dist recur class Prosigna
Display Name
Breast cancer 10-year risk of distant recurrence classification Prosigna Ql [Interp]

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.52
Order vs. Observation
Observation

Normative Answer List LL3198-0

Source: Laboratory Corporation of America

Answer Code Score Answer ID
High risk LA19541-4
Intermediate risk LA22380-2
Low risk LA19542-2

Member of these Panels

LOINC Long Common Name
76546-1 Breast cancer 10-year risk of distant recurrence panel by Prosigna

Language Variants Get Info

zh-CNChinese (CHINA)
乳腺癌远处转移 10 年风险分类:印象:时间点:^患者:序数型:Prosigna
fr-FRFrench (FRANCE)
Breast cancer 10Y risk of distant recurrence classification:Imp:Pt:^Patient:Ord:Prosigna
it-ITItalian (ITALY)
Tumore della mammella, rischio 10 anni di recidive tumorali, classificazione:Imp:Pt:^Paziente:Ord:Prosigna
es-ESSpanish (SPAIN)
Clasificación del riesgo de recurrencia a 10 años en el cáncer de mama:Impresión/interpretación del estudio:Punto temporal:^paciente:Ord:Sustrato 2,3-14C succinato

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=76545-3