LOINC
Version 2.72

77021-4Fetal Y chromosome [Presence] based on Plasma cell-free DNA by SequencingActive

Part Description

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977.[PMID:271968] Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost.[PMID:18576944] Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template.[PMID:20858600] Source: Regenstrief LOINC

Fully-Specified Name

Component
Fetal Y chromosome
Property
PrThr
Time
Pt
System
Plas.cfDNA
Scale
Ord
Method
Sequencing

Additional Names

Short Name
Fet Y Chrom Plas.cfDNA Ql
Display Name
Y chromosome Sequencing Ql (cfDNA)
Consumer Name Alpha
Fetal Y chromosome

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.66
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Added "Fetal" to Component to clarify that the result is about the fetus.
Order vs. Observation
Observation
Common US Lab Results Rank
3000
Common SI Lab Results Rank
3000

Member of these Panels

LOINC Long Common Name
77018-0 Noninvasive prenatal fetal 13 and 18 and 21 aneuploidy panel - Plasma cell-free DNA by Sequencing
92901-8 Noninvasive prenatal fetal aneuploidy and microdeletion panel - Plasma cell-free DNA by Sequencing

Language Variants Get Info

zh-CNChinese (China)
胎儿染色体 Y:存在情况或阈值:时间点:血浆.cfDNA:序数型:序列测定
nl-NLDutch (Netherlands)
foetaal Y-chromosoom:aanwezigheid:moment:plasma.celvrij DNA:ordinaal:sequencing
fr-FRFrench (France)
Chromosome foetal Y:Présence/Seuil:Ponctuel:Plasma avec ADN libre circulant:Qualitatif:Séquençage
it-ITItalian (Italy)
Cromosoma Y:PrThr:Pt:Plasma.DNA libero circolante:Ord:Sequenziamento
es-MXSpanish (Mexico)
Cromosoma Y fetal:Presencia o umbral:Punto temporal:ADN libre de células plasmáticas:Ordinal:Secuenciación
es-ESSpanish (Spain)
Cromosoma fetal Y:PrThr:Punto temporal:ADN en plasma libre de células:Ord:Secuenciación

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=77021-4