77141-0Alkaline phosphatase [Enzymatic activity/volume] in Serum, Plasma or BloodActive
Part Descriptions
LP15346-7 Alkaline phosphatase
An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1.
Source: National Library of Medicine, MeSH 2006
LP15346-7 Alkaline phosphatase
Alkaline phosphatase (ALP, ALKP) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. ALP is present in all tissues throughout the entire body, but is particularly concentrated in liver, bile duct, kidney, bone, and the placenta. Humans and most other mammals contain the following ALP isozymes: ALPI (intestinal), ALPL (tissue non-specific, liver/bone/kidney), and ALPP (placental, aka Regan isozyme).
The normal range of alkaline phosphatase is 20 to 140 IU/L. High ALP levels are present in children and pregnant women, if bile ducts are blocked, and in the presence of osteoblast activity, such as with Paget's disease of the bone. Lowered levels of ALP are less common than elevated levels and occurs in various conditions, including aplastic and pernicious anemias, chronic myelogenous leukemia, Wilson's disease, children with severe enteritis, and postmenopausal women on estrogen therapy for osteoporosis.
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Source: Wikipedia, Alkaline phosphatase (Wikipedia)
Fully-Specified Name
- Component
- Alkaline phosphatase
- Property
- CCnc
- Time
- Pt
- System
- Ser/Plas/Bld
- Scale
- Qn
- Method
Additional Names
- Short Name
- ALP SerPlBld-cCnc
- Display Name
- ALP (S/P/Bld) [Catalytic activity/Vol]
- Consumer Name Alpha
- Alkaline phosphatase, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.52
- Last Updated
- Version 2.73
- Change Reason
- Release 2.68: DefinitionDescription: Moved to Mapping Guidance section.
- Order vs. Observation
- Both
- Common US Lab Results Rank
- 9179
Reference Information
Type | Source | Reference |
---|---|---|
Webcontent | Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. | Alkaline Phosphatase (ALP) |
Mapping Guidance | LOINC | This term was made to accommodate a laboratory system outside of the US. LOINC currently discourages the use of specimens combining ser/plas and blood in one term (as ser/plas/bld) for two reasons. First, practices usually want to distinguish the two on ordering since whole blood usually implies a point of care test and ser/plas usually implies sending to another location. Second, whole blood tests are usually classified as low complexity (waived) under CLIA regulations, and because waived tests are excluded from the annual COLA report of testing volume (required by the Centers for Medicare and Medicaid Services) and ser/plas tests are not, the two have to be distinguished. |
Member of these Groups
LG5665-7 | Alkaline phosphatase| |
Language Variants Get Info
- zh-CNChinese (China)
- 碱性磷酸酶:
催化浓度: 时间点: 血清/血浆/全血: 定量型: - nl-NLDutch (Netherlands)
- alkalische fosfatase:
enzymatische activiteit/volume: moment: serum of plasma of bloed: kwantitatief: - et-EEEstonian (Estonia)
- Aluseline fosfataas:
CCnc: Pt: S/P/B: Qn: - fr-BEFrench (Belgium)
- Phosphatase alcaline:
Concentration catalytique: Temps ponctuel: Sérum/Plasma/Sang: Quantitatif: - fr-CAFrench (Canada)
- Phosphatase alcaline:
Concentration catalytique: Temps ponctuel: Sérum/Plasma/Sang: Quantitatif: - fr-FRFrench (France)
- Phosphatases alcalines:
Catalytique/Volume: Ponctuel: Sérum/Plasma/Sang: Numérique: - it-ITItalian (Italy)
- Fosfatasi alcalina:
CCnC: Pt: Siero/Plasma/Sangue: Qn: - pl-PLPolish (Poland)
- Fosfataza zasadowa:
Stężenie katalityczne: Punkt w czasie: Surowica, osocze lub krew: ilościowy: - ru-RURussian (Russian Federation)
- Щелочная фосфатаза:
КаталКонц: ТчкВрм: Сыв/Плаз/Кр: Колич: - es-MXSpanish (Mexico)
- Fosfatasa alcalina:
Concentración catalítica: Punto temporal: Suero, plasma o sangre: Cuantitativo: - es-ESSpanish (Spain)
- Fosfatasa alcalina total:
Concentración Catalítica: Punto temporal: Suero, Plasma o Sangre: Qn: - tr-TRTurkish (Turkey)
- Alkalen fosfataz:
KtlKons: Zmlı: Ser/Plaz/Kan: Kant:
Example Units
Unit | Source |
---|---|
U/L | Example UCUM Units |
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=77141-0
LOINC Copyright
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