Version 2.76

Part Descriptions

LP15346-7   Alkaline phosphatase
An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1. Source: National Library of Medicine, MeSH 2006

LP15346-7   Alkaline phosphatase
Alkaline phosphatase (ALP, ALKP) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. ALP is present in all tissues throughout the entire body, but is particularly concentrated in liver, bile duct, kidney, bone, and the placenta. Humans and most other mammals contain the following ALP isozymes: ALPI (intestinal), ALPL (tissue non-specific, liver/bone/kidney), and ALPP (placental, aka Regan isozyme).

The normal range of alkaline phosphatase is 20 to 140 IU/L. High ALP levels are present in children and pregnant women, if bile ducts are blocked, and in the presence of osteoblast activity, such as with Paget's disease of the bone. Lowered levels of ALP are less common than elevated levels and occurs in various conditions, including aplastic and pernicious anemias, chronic myelogenous leukemia, Wilson's disease, children with severe enteritis, and postmenopausal women on estrogen therapy for osteoporosis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Alkaline phosphatase (Wikipedia)

Reference Information

Type Source Reference
Mapping Guidance LOINC This term was made to accommodate a laboratory system outside of the US. LOINC currently discourages the use of specimens combining ser/plas and blood in one term (as ser/plas/bld) for two reasons. First, practices usually want to distinguish the two on ordering since whole blood usually implies a point of care test and ser/plas usually implies sending to another location. Second, whole blood tests are usually classified as low complexity (waived) under CLIA regulations, and because waived tests are excluded from the annual COLA report of testing volume (required by the Centers for Medicare and Medicaid Services) and ser/plas tests are not, the two have to be distinguished.
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Alkaline Phosphatase (ALP)

Fully-Specified Name

Component
Alkaline phosphatase
Property
CCnc
Time
Pt
System
Ser/Plas/Bld
Scale
Qn
Method

Additional Names

Short Name
ALP SerPlBld-cCnc
Display Name
ALP (S/P/Bld) [Catalytic activity/Vol]
Consumer Name Alpha Get Info
Alkaline phosphatase, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.73
Change Reason
Release 2.68: DefinitionDescription: Moved to Mapping Guidance section.
Order vs. Observation
Both
Common Test Rank Get Info
9179

Member of these Groups Get Info

LOINC Group Group Name
LG5665-7 Alkaline phosphatase|CCnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Fosfatasa alcalina total:Concentración Catalítica:Punto temporal:Suero, Plasma o Sangre:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Fosfatasa alcalina:Concentración catalítica:Punto temporal:Suero, plasma o sangre:Cuantitativo:
et-EE Estonian (Estonia) Aluseline fosfataas:CCnc:Pt:S/P/B:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma Seerum või plasma või veri Veri
fr-CA French (Canada) Phosphatase alcaline:Concentration catalytique:Temps ponctuel:Sérum/Plasma/Sang:Quantitatif:
fr-FR French (France) Phosphatases alcalines:Catalytique/Volume:Ponctuel:Sérum/Plasma/Sang:Numérique:
fr-BE French (Belgium) Phosphatase alcaline:Concentration catalytique:Temps ponctuel:Sérum/Plasma/Sang:Quantitatif:
Synonyms: ALP
it-IT Italian (Italy) Fosfatasi alcalina:CCnC:Pt:Siero/Plasma/Sangue:Qn:
Synonyms: Chimica Concentrazione Catalitica Plasma Plasma o Sangue Punto nel tempo (episodio) Sangue Siero Siero o Plasma Siero,Plasma o Sangue
nl-NL Dutch (Netherlands) alkalische fosfatase:enzymatische activiteit/volume:moment:serum of plasma of bloed:kwantitatief:
pl-PL Polish (Poland) Fosfataza zasadowa:stężenie katalityczne:punkt w czasie:surowica, osocze lub krew:ilościowy:
ru-RU Russian (Russian Federation) Щелочная фосфатаза:КаталКонц:ТчкВрм:Сыв/Плаз/Кр:Колич:
Synonyms: Каталитическая концентрация Количественный Кровь Плазма Сыворотка Сыворотка или Плазма Сыворотка, Плазма или Кровь Точка во времени;Момент
tr-TR Turkish (Turkey) Alkalen fosfataz:KtlKons:Zmlı:Ser/Plaz/Kan:Kant:
zh-CN Chinese (China) 碱性磷酸酶:催化浓度:时间点:血清/血浆/全血:定量型:
Synonyms: ALKP;ALP;AP;总碱性磷酸酯酶;总碱性磷酸酶;总碱磷酶;碱性磷酸酯酶;碱性磷酸酯酶.总计;碱性磷酸酶.总计;碱磷酶;碱磷酶.总计 催化浓度(单位体积);单位体积内酶的单位数 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 碱 磷酸单酯酶 磷酸酶 血;血液 血浆或全血;血浆/血液;血浆或血液 血清、血浆或全血;血清、血浆或血液;血清/血浆/血液 血清或血浆

Example Units

Unit Source
U/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=77141-0