LOINC
Version 2.70

77141-0Alkaline phosphatase [Enzymatic activity/volume] in Serum, Plasma or BloodActive

Part Descriptions

LP15346-7   Alkaline phosphatase
An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1. Source: National Library of Medicine, MeSH 2006

LP15346-7   Alkaline phosphatase
Alkaline phosphatase (ALP, ALKP) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. ALP is present in all tissues throughout the entire body, but is particularly concentrated in liver, bile duct, kidney, bone, and the placenta. Humans and most other mammals contain the following ALP isozymes: ALPI (intestinal), ALPL (tissue non-specific, liver/bone/kidney), and ALPP (placental, aka Regan isozyme).

The normal range of alkaline phosphatase is 20 to 140 IU/L. High ALP levels are present in children and pregnant women, if bile ducts are blocked, and in the presence of osteoblast activity, such as with Paget's disease of the bone. Lowered levels of ALP are less common than elevated levels and occurs in various conditions, including aplastic and pernicious anemias, chronic myelogenous leukemia, Wilson's disease, children with severe enteritis, and postmenopausal women on estrogen therapy for osteoporosis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Alkaline phosphatase (Wikipedia)

Fully-Specified Name

Component
Alkaline phosphatase
Property
CCnc
Time
Pt
System
Ser/Plas/Bld
Scale
Qn
Method

Additional Names

Short Name
ALP SerPlBld-cCnc
Display Name
ALP (S/P/Bld) [Catalytic activity/Vol]
Consumer Name Alpha
Alkaline phosphatase, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.68
Change Reason
Release 2.68: DefinitionDescription: Moved to Mapping Guidance section.
Order vs. Observation
Both

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2001-2019 American Association for Clinical Chemistry Alkaline Phosphatase (ALP)
Mapping Guidance LOINC This term was made to accommodate a laboratory system outside of the US. LOINC currently discourages the use of specimens combining ser/plas and blood in one term (as ser/plas/bld) for two reasons. First, practices usually want to distinguish the two on ordering since whole blood usually implies a point of care test and ser/plas usually implies sending to another location. Second, whole blood tests are usually classified as low complexity (waived) under CLIA regulations, and because waived tests are excluded from the annual COLA report of testing volume (required by the Centers for Medicare and Medicaid Services) and ser/plas tests are not, the two have to be distinguished.

Member of these Groups

LG5665-7 Alkaline phosphatase|CCnc|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
碱性磷酸酶:催化浓度:时间点:血清/血浆/全血:定量型:
nl-NLDutch (Netherlands)
alkalische fosfatase:enzymatische activiteit/volume:moment:serum of plasma of bloed:kwantitatief:
et-EEEstonian (Estonia)
Aluseline fosfataas:CCnc:Pt:S/P/B:Qn:
fr-BEFrench (Belgium)
Phosphatase alcaline:Concentration catalytique:Temps ponctuel:Sérum/Plasma/Sang:Quantitatif:
fr-CAFrench (Canada)
Phosphatase alcaline:Concentration catalytique:Temps ponctuel:Sérum/Plasma/Sang:Quantitatif:
fr-FRFrench (France)
Phosphatases alcalines:Catalytique/Volume:Ponctuel:Sérum/Plasma/Sang:Numérique:
it-ITItalian (Italy)
Fosfatasi alcalina:CCnC:Pt:Siero/Plasma/Sangue:Qn:
ru-RURussian (Russian Federation)
Щелочная фосфатаза:КаталКонц:ТчкВрм:Сыв/Плаз/Кр:Колич:
es-ESSpanish (Spain)
Fosfatasa alcalina total:Concentración Catalítica:Punto temporal:Suero, Plasma o Sangre:Qn:
tr-TRTurkish (Turkey)
Alkalen fosfataz:KtlKons:Zmlı:Ser/Plaz/Kan:Kant:

Example Units

Unit Source
U/L Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=77141-0