LOINC
Version 2.67

77253-3Microalbumin/Creatinine [Ratio] in Urine by Detection limit <= 1.0 mg/LActive

Term Description

Measures the albumin excretion in urine to aid in the early detection of kidney disease (and increased risk of cardiovascular events) for patients with diabetes. Normal 24 hour urine albumin excretion is less than 30 mg/day in adults. 24-hour urine excretion results between 30-300 mg/day are defined as microalbuminuria (MAU) which may occur with kidney damage. While a 24-hour urine is preferred, a random urine sample can be tested as well.
Source: Regenstrief LOINC

Part Descriptions

LP6118-6   Albumin
A non-glycosylated protein that is synthesized in the liver parenchymal cells, regulated by colloid osmotic pressure from interstitial fluid surrounding hepatocytes, and catabolized in nearly all organs. Albumin comprises >50% of plasma proteins in plasma, CSF and urine, and therefore is a key contributor to intravascular oncotic pressure and regulating fluid concentration in tissues. Albumin also binds and transports a variety of endogenous substances and medications. Serum albumin measurement is a reflection of hydration and nutritional status, blood oncotic pressure, liver and kidney function, and other chronic diseases, and the ratio of albumin in the CSF and serum can be used to evaluate blood brain barrier disorders. [Tietz] Urine albumin of less than 30 mg/day is considered normal. Microalbuminuria is defined as urine albumin of 30-300 mg/day and is an early sign of kidney damage from disorders such as diabetes or hypertension. Albuminuria is urine albumin >300 mg/day and is associated with overt kidney disease. [PMID: 25512779] Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Regenstrief LOINC, Tietz

LP70454-1   Detection limit <= 1.0 mg/L
Limit of detection is the lowest analyte concentration at which detection is feasible for the assay method. [PMCID: 2556583] Source: Regenstrief LOINC

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component
Albumin/Creatinine
Property
Ratio
Time
Pt
System
Urine
Scale
Qn
Method
Detection limit <= 1.0 mg/L

Additional Names

Short Name
Microalbumin/Creat Ur DL<=1mg/L-Rto
Display Name
Albumin/Creatinine DL <= 1.0 mg/L (U) [Ratio]

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.54
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
79544-3 HEDIS 2016 Value Sets
82955-6 HEDIS 2017 Value Sets
87625-0 HEDIS 2018 Value Sets
90766-7 HEDIS 2019 Value Sets
94137-7 HEDIS 2020 Value Sets

Member of these Groups

LG37540-8 Microalbumin|Ratio|Urine

Language Variants Get Info

zh-CNChinese (CHINA)
白蛋白/肌酐:比率:时间点:尿液:定量型:检测极限 <= 1.0 mg/L
nl-NLDutch (NETHERLANDS)
albumine/creatinine:verhouding:moment:urine:kwantitatief:detectielimiet <= 1,0 mg/L
fr-BEFrench (BELGIUM)
Albumine/Créatinine:Ratios:Temps ponctuel:Urine:Quantitatif:Limite de détection <= 1,0 mg/L
fr-CAFrench (CANADA)
Albumine/Créatinine:Ratios:Temps ponctuel:Urine:Quantitatif:Limite de détection <= 1,0 mg/L
fr-FRFrench (FRANCE)
Albumine/créatinine:Ratio:Ponctuel:Urine:Numérique:Limite de détection<=1,0mg/L
it-ITItalian (ITALY)
Albumina/Creatinina:Rapporto:Pt:Urine:Qn:Limite di rilevabilitá <= 1,0 mg/L
es-ESSpanish (SPAIN)
Albúmina/Creatinina:Fracción:Punto temporal:Orina:Qn:Límite de detección = 1,0 mg/L
tr-TRTurkish (TURKEY)
Albumin/Kreatinin:Oran:Zmlı:İdrar:Kant:Saptama sınırı <= 1.0 mg/L

Example Units

Unit Source
mg/mmol{creat} Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=77253-3