LOINC
Version 2.67

77353-1Noninvasive colorectal cancer DNA and occult blood screening [Interpretation] in Stool NarrativeActive

Term Description

This term was created for, but is not limited in use to, Exact Sciences' Cologuard DNA screening test for colorectal cancer. The Cologuard algorithm includes two laboratory procedures performed on a single stool specimen: 1) detection and quantification of fecal occult blood using ELISA; and 2) detection of multiple genetic biomarkers (NDRG4 and BMP3 methylation targets, seven KRAS point mutations, and beta actin as a proxy for the total amount of human DNA in each sample) using magnetic bead based oligonucleotide hybrid capture to isolate the biomarkers followed by quantitative real-time target and signal amplification. The occult blood and genetic biomarker results are subsequently entered into a logistic regression model, and the results from this model are used to calculate a composite score from which the final binary result (positive, negative) is determined. [PMID: 24645800]
Source: Regenstrief LOINC

Fully-Specified Name

Component
Noninvasive colorectal cancer DNA+occult blood screening
Property
Imp
Time
Pt
System
Stool
Scale
Nar
Method

Additional Names

Short Name
Noninv colon ca DNA+occ bld scrn Stl-Imp
Display Name
Noninvasive colorectal cancer DNA and occult blood screening Nar (Stl) [Interp]

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.52
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
82955-6 HEDIS 2017 Value Sets
87625-0 HEDIS 2018 Value Sets
90766-7 HEDIS 2019 Value Sets
94137-7 HEDIS 2020 Value Sets

Language Variants Get Info

zh-CNChinese (CHINA)
无创性结直肠癌 DNA+潜血筛查:印象:时间点:大便:叙述型:
fr-FRFrench (FRANCE)
Noninvasive colorectal cancer DNA+occult blood screening:Imp:Pt:Stool:Nar:
it-ITItalian (ITALY)
Screening non invasivo DNA+sangue occulto tumore colorettale:Imp:Pt:Feci:Nar:
es-ESSpanish (SPAIN)
Screening no invasivo de cancer colorectal ADN+sangre oculta:Impresión/interpretación del estudio:Punto temporal:Heces:Narrativo:
tr-TRTurkish (TURKEY)
Noninvaziv kolorektal kanser DNA+gaitada gizli kan tarama:İzlnm:Zmlı:Dışkı:Öykü:

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=77353-1