Version 2.76

Term Description

This term was created for, but not limited in use to, the MONOFLUO KIT CMV for the detection of cytomegalovirus by indirect immunofluorescence, using using monoclonal antibodies specific for this virus.
Source: Regenstrief LOINC

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Cytomegalovirus Ag
Property
PrThr
Time
Pt
System
BAL
Scale
Ord
Method
IF

Additional Names

Short Name
CMV Ag BAL Ql IF
Display Name
CMV Ag IF Ql (BAL)
Consumer Name Alpha Get Info
Cytomegalovirus (CMV) antigen, Bronchoalveolar lavage specimen

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
87964-3 Respiratory pathogens panel - Bronchoalveolar lavage by Immunofluorescence

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Citomegalovirus Antígeno:PrThr:Punto temporal:Lavado broncoalveolar:Ord:Inmunofluorescencia (IF)
es-MX Spanish (Mexico) Citomegalovirus Ag:Presencia o umbral:Punto temporal:Lavado broncoalveolar:Ordinal:Inmunofluorescencia (IF)
et-EE Estonian (Estonia) Tsütomegaloviirus antigeen:PrThr:Pt:BalF:Ord:IF
Synonyms: Järgarvuline Juhuslik
fr-CA French (Canada) Cytomégalovirus , Ag:Présence-Seuil:Temps ponctuel:Lavage broncho-alvéolaire:Ordinal:Immunofluorescence
fr-FR French (France) Cytomégalovirus Ag:Présence/Seuil:Ponctuel:Liquide bronchoalvéolaire:Qualitatif:Immunofluorescence
fr-BE French (Belgium) Cytomégalovirus Ag:PrThr:Temps ponctuel:Lavage broncho-alvéolaire:Ordinal:Immunofluorescence
Synonyms: Antigène CMV
it-IT Italian (Italy) Citomegalovirus , Ag:PrThr:Pt:BAL:Ord:IF
Synonyms: Immunofluorescenza (IF) Lavaggio Bronco Alveolare Microbiologia Presenza o Soglia Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) Cytomegalovirus Ag:aanwezigheid:moment:bronchoalveolaire wassing:ordinaal:immunofluorescentie
Synonyms: antigeen IF
pl-PL Polish (Poland) Wirus cytomegalii Ag:granica wykrywalności:punkt w czasie:popłuczyny oskrzelowo-pęcherzykowe:półilościowy:immunofluorescencja
Synonyms: Antygen wirusa cytomegalii Cytomegalowirus
ru-RU Russian (Russian Federation) Цитомегаловирус Аг:PrThr:ТчкВрм:БАЛ:Пор:ИФ
Synonyms: Бронхоальвеолярный лаваж Иммунофлюоресценция (ИФ) Порядковый Точка во времени;Момент
tr-TR Turkish (Turkey) Cytomegalovirus Ag:MevcEşik:Zmlı:BAL:Srl:IF
Synonyms: Antijen Bronkoalveoler lavaj İmmünflorerans Mevcut
zh-CN Chinese (China) 巨细胞病毒 抗原:存在情况或阈值:时间点:支气管肺泡灌洗液:序数型:免疫荧光法
Synonyms: Ag Ag IF CMV Ag CMV 抗原 CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒 DFA IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 巨细胞病毒 Ag 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 抗原免疫荧光检测 抗原免疫荧光测定 支气管肺泡洗液 时刻;随机;随意;瞬间 直接免疫荧光分析 直接免疫荧光检测 直接免疫荧光测定

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