LOINC
Version 2.67

77388-7Cytomegalovirus Ag [Presence] in Bronchoalveolar lavage by ImmunofluorescenceActive

Term Description

This term was created for, but not limited in use to, the MONOFLUO KIT CMV for the detection of cytomegalovirus by indirect immunofluorescence, using using monoclonal antibodies specific for this virus.
Source: Regenstrief LOINC

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Cytomegalovirus Ag
Property
PrThr
Time
Pt
System
BAL
Scale
Ord
Method
IF

Additional Names

Short Name
CMV Ag BAL Ql IF
Display Name
CMV Ag IF Ql (BAL)

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
87964-3 Respiratory pathogens panel - Bronchoalveolar lavage by Immunofluorescence

Language Variants Get Info

zh-CNChinese (CHINA)
巨细胞病毒 抗原:存在情况或阈值:时间点:支气管肺泡灌洗液:序数型:免疫荧光法
nl-NLDutch (NETHERLANDS)
Cytomegalovirus Ag:aanwezigheid:moment:bronchoalveolaire wassing:ordinaal:immunofluorescentie
et-EEEstonian (ESTONIA)
Tsütomegaloviirus antigeen:PrThr:Pt:BalF:Ord:IF
fr-BEFrench (BELGIUM)
Cytomégalovirus Ag:PrThr:Temps ponctuel:Lavage broncho-alvéolaire:Ordinal:Immunofluorescence
fr-CAFrench (CANADA)
Cytomégalovirus , Ag:Présence-Seuil:Temps ponctuel:Lavage broncho-alvéolaire:Ordinal:Immunofluorescence
fr-FRFrench (FRANCE)
Cytomégalovirus Ag:Présence/Seuil:Ponctuel:Liquide bronchoalvéolaire:Qualitatif:Immunofluorescence
it-ITItalian (ITALY)
Citomegalovirus , Ag:PrThr:Pt:BAL:Ord:IF
ru-RURussian (RUSSIAN FEDERATION)
Цитомегаловирус Аг:PrThr:ТчкВрм:БАЛ:Пор:ИФ
es-ESSpanish (SPAIN)
Citomegalovirus Antígeno:PrThr:Punto temporal:Lavado broncoalveolar:Ord:Inmunofluorescencia (IF)
tr-TRTurkish (TURKEY)
Cytomegalovirus Ag:MevcEşik:Zmlı:BAL:Srl:IF

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=77388-7