LOINC
Version 2.67

77959-5Yellow fever virus ns5 gene [Presence] in Cerebral spinal fluid by NAA with non-probe detectionActive

Term Description

This assay comprises qRT-PCR targeting the ns5 gene in the yellow fever backbone followed by melt curve analysis, which identifies DNA fragments with different nucleotide compositions based on their unique melting temperature. [PMID: 18501437] CSF testing is indicated for suspected adverse neurological reactions to the vaccine against yellow fever. Genome detection of CSF yellow fever vaccine in this context is considered diagnostic. In suspected patients, detection of antibodies against yellow fever in CSF should also be requested.
Source: Regenstrief LOINC

Part Description

LP203622-8   Yellow fever virus ns5 gene
Yellow fever (also called yellow jack, black vomit or vomito negro in Spanish, or sometimes American Plague) is an acute viral disease. It is an important cause of hemorrhagic illness in many African and South American countries despite existence of an effective vaccine. The yellow in the disease name refers to the jaundice that affects some patients. Yellow fever has been a source of several devastating epidemics. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Yellow fever virus (Wikipedia)

Fully-Specified Name

Component
Yellow fever virus ns5 gene
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
Non-probe.amp.tar

Additional Names

Short Name
YFV ns5 gene CSF Ql NAA+non-probe
Display Name
Yellow fever virus ns5 gene NAA+non-probe Ql (CSF)

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.63
Change Reason
Changed Method from "Melt.amp.tar" to "Non-probe.amp.tar", which includes other non-probe based detection methods while still distinguishing from probe-based methods.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Groups

LG32769-8 Yellow fever virus

Language Variants Get Info

zh-CNChinese (CHINA)
黄热病病毒 ns5 基因:存在情况或阈值:时间点:脑脊液:序数型:非探针法.基因扩增.靶向
it-ITItalian (ITALY)
Virus della febbre gialla, gene ns5:PrThr:Pt:LCS:Ord:Non-sonda.amp.tar
es-ESSpanish (SPAIN)
gen ns5 del virus de la fiebre amarilla:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Amplificación del objetivo no basado en sonda

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=77959-5