LOINC
Version 2.71

78444-7Hepatitis A virus IgG+IgM Ab [Units/volume] in Serum or Plasma by ImmunoassayActive

Term Description

This term was created for, but not limited in use to, the submitter's Roche cobas Total antibodies (IgM and IgG) to the hepatitis A virus test kit, for the determination of total antibodies to the hepatitis A virus.
Source: Regenstrief LOINC

Part Descriptions

LP16708-7   Hepatitis A virus
Hepatitis A virus (Hep A or HAV) is an RNA virus that causes an acute infectious disease of the liver and is usually spread by the fecal-oral route. It is transmitted by ingestion of contaminated food or water or through direct contact with an infectious person. In developing countries, and in regions with poor hygiene standards, the incidence of infection with this virus is high. HAV infection produces a self-limited disease that usually does not result in chronic infection or chronic liver disease. Overall occurrence acute liver failure from Hepatitis A is rare (approx. 0.5%). The risk for symptomatic infection is directly related to age, with >80% of adults having symptoms compatible with acute viral hepatitis and the majority of children having either asymptomatic or unrecognized infection. Antibody produced in response to HAV infection persists for life and confers protection against reinfection. The disease can be prevented by vaccination, and hepatitis A vaccine has been proven effective in controlling outbreaks worldwide.

Although HAV is excreted in the feces towards the end of the incubation period, specific diagnosis is made by the detection of HAV-specific IgM antibodies in the blood. IgM antibody is only present in the blood following an acute hepatitis A infection. It is detectable from one to two weeks after the initial infection and persists for up to 14 weeks. The presence of IgG antibody in the blood means that the acute stage of the illness is past and the person is immune to further infection. IgG antibody to HAV is also found in the blood following vaccination and tests for immunity to the virus are based on the detection of this antibody. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Hepatitis A virus (Wikipedia)

LP16708-7   Hepatitis A virus
Hepatitis A virus (HAV) is a small, non-enveloped single-stranded RNA virus that belongs to the Picornaviridae family, genus Hepatovirus. HAV has six genotypes (I to VI) in which genotypes I to III are human isolates and IV to VI are only simian isolates. Genotypes I to III are subdivided into groups A and B. Genotype I is the most frequently reported. [PMID: 15914081] The clinical manifestations of HAV infection can vary significantly and range from asymptomatic infection, usually seen in young children, to fulminant hepatitis, which can result in death. HAV has a global distribution, and transmission primarily occurs by the fecal-oral route. The risk of HAV transmission through blood products is very low, but there have been some reports of transmission through plasma products, mainly coagulation factors. [PMID: 12186933] [PMID: 1318940] Source: Regenstrief LOINC

Fully-Specified Name

Component
Hepatitis A virus Ab.IgG+IgM
Property
ACnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method
IA

Additional Names

Short Name
HAV IgG+IgM SerPl IA-aCnc
Display Name
HAV IgG+IgM IA Qn
Consumer Name Alpha
Hepatitis A virus (HAV) IgG+IgM, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.54
Last Updated
Version 2.56
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups

LG32762-3 Hepatitis A virus

Language Variants Get Info

zh-CNChinese (China)
甲型肝炎病毒 抗体.IgG+IgM:任意型浓度:时间点:血清/血浆:定量型:免疫测定法
nl-NLDutch (Netherlands)
Hepatitis A-virus As.IgG + IgM:eenheid/volume:moment:serum of plasma:kwantitatief:immunoassay
et-EEEstonian (Estonia)
A-hepatiidi viirus antikehad.IgG+IgM:Acnc:Pt:S/P:Qn:IA
fr-BEFrench (Belgium)
Virus de l'hépatite A Anticorps.IgG+IgM:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:IA
fr-CAFrench (Canada)
Virus de l'hépatite A , IgG+IgM:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:IA
fr-FRFrench (France)
Hépatite A virus Ac IgG+IgM:Arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:Immunoanalyse
de-DEGerman (Germany)
Hepatitis-A-Virus Ak.IgG+IgM:AKnz:Pkt:Ser/Plas:Qn:IA
it-ITItalian (Italy)
Epatite A, virus , Ab.IgG+IgM:ACnc:Pt:Siero/Plasma:Qn:IA
ru-RURussian (Russian Federation)
Гепатита А вирус Ат.IgG+IgM:ПроизвКонц:ТчкВрм:Сыв/Плаз:Колич:IA
es-ESSpanish (Spain)
Virus de la Hepatitis A IgG+IgM:Concentración arbitraria:Punto temporal:Suero o Plasma:Qn:IA
tr-TRTurkish (Turkey)
Hepatit A virüsü Ab.IgG+IgM:SçKons:Zmlı:Ser/Plaz:Kant:İA

Example Units

Unit Source
[IU]/L Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=78444-7