79209-3t(2;3)(q13;p25)(PAX8, PPARG) fusion transcript [Presence] in Tissue by Molecular genetics methodActive
Part Description
LP200416-8 t(2;3)(q13;p25)(PAX8,PPARG)
The PAX8/PPARG (paired box 8/peroxisome proliferator-activated receptor gamma) gene rearrangement is created by a translocation between chromosome arms 2q and 3p where the entire coding region of the PPARG transcription factor gene is fused with the first 8 to 10 exons of the PAX8 gene.[PMID:10958784] Translocations of the PAX8/PPARG genes play a role in the pathogenesis of some follicular thyroid carcinomas and follicular-variant papillary thyroid carcinoma.[PMID:20056739] Several testing methods are used to detect the rearrangement, including fluorescence in situ hybridization (FISH), immunohistochemistry (IHC), and reverse-transcription PCR (RT-PCR).
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Source: Regenstrief LOINC, PAX8
Fully-Specified Name
- Component
- t(2;3)(q13;p25)(PAX8,PPARG) fusion transcript
- Property
- PrThr
- Time
- Pt
- System
- Tiss
- Scale
- Ord
- Method
- Molgen
Additional Names
- Short Name
- t(2;3)(PAX8,PPARG) Tiss Ql
- Display Name
- t(2;3)(q13;p25)(PAX8,PPARG) fusion transcript Molgen Ql (Tiss)
- Consumer Name Alpha
- t(2;3)(q13;p25)(PAX8,PPARG) fusion transcript analysis, Tissue
Example Answer List LL744-4
Source: Regenstrief Institute
Answer | Code | Score | Answer ID |
---|---|---|---|
Detected | LA11882-0 | ||
Not detected | LA11883-8 |
Basic Attributes
- Class
- MOLPATH.TRNLOC
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Language Variants Get Info
- zh-CNChinese (China)
- t(2;
3)(q13; p25)(PAX8,PPARG) 融合转录物: 存在情况或阈值: 时间点: 组织与涂片: 序数型: 分子遗传学类实验室方法 - nl-NLDutch (Netherlands)
- t(2;
3)(q13; p25)(PAX8,PPARG) fusietranscript: aanwezigheid: moment: weefsel en uitstrijkjes: ordinaal: moleculair genetisch onderzoek - fr-FRFrench (France)
- t(2;
3)(q13; p25)(PAX8,PPARG) transcrit de fusion: Présence/Seuil: Ponctuel: Tissu: Qualitatif: Biologie moléculaire - it-ITItalian (Italy)
- t(2;
3)(q13; p25)(PAX8,PPARG) , trascritto di fusione: PrThr: Pt: Tessuto: Ord: Molgen - es-MXSpanish (Mexico)
- t (2;
3) (q13; p25) (PAX8, PPARG) transcripción de fusión: Presencia o umbral: Punto temporal: Tejido y frotis: Ordinal: Genética molecular - es-ESSpanish (Spain)
- t(2;
3)(q13; p25)(PAX8,PPARG) Tránscritos de fusión: PrThr: Punto temporal: Tejido: Ord: Genética molecular - tr-TRTurkish (Turkey)
- t(2;
3)(q13; p25)(PAX8,PPARG) füzyon transkript: MevcEşik: Zmlı: Doku: Srl: Molgen
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79209-3
LOINC Copyright
Copyright © 2022 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright