Version 2.77

Term Description

Testing for folate and its metabolites as well as tryptophan and its metabolites in CSF can be useful in distinguishing among various central nervous system disorders associated with folate deficiency. Low folate levels are associated with inborn errors of metabolism, including cerebral folate deficiency (CFD), a neurological syndrome that occurs around 2-4 months of age and is primarily associated with associated with low levels of 5-methyltetrahydrofolate (5-MTHF) in the CSF with normal folate levels in the plasma and red blood cells. PMID: 19260931 Low folate levels are also associated with depression and dementia in elderly patients. PMID: 11183038 Serotonin, which is formed from tryptophan, may be the link between folate and depression or dementia. Many patients with neuropsychiatric disorders and folate deficiency have also been found to have low levels of 5-hydroxyindoleacetic acid (5-HIAA, a serotonin metabolite), and patients with 5,10-methylenetetrahydrofolate reductase (MTHFR) deficiency also have decreased serotonin synthesis. [PMCID: 1810582]
Source: Regenstrief LOINC

Fully-Specified Name

Folate & tryptophan & metabolites pattern

Additional Names

Short Name
Folate + Tryp + Metabs Pattern CSF-Imp
Display Name
Folate and tryptophan and metabolites pattern Nar (CSF) [Interp]
Consumer Name Alpha Get Info
Interpretation of Folate and Tryptophan and Metabolites pattern test result, Spinal fluid

Basic Attributes

First Released
Version 2.54
Last Updated
Version 2.54
Order vs. Observation

Member of these Panels

LOINC Long Common Name
79572-4 Folate and tryptophan and metabolites panel - Cerebral spinal fluid

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Patrón de folato y triptofano y metabolitos:Impresión/interpretación del estudio:Punto temporal:Líquido Cefalorraquideo:Narrativo:
es-MX Spanish (Mexico) Patrón de folato, triptófano y metabolitos:Impresión / interpretación del estudio:Punto temporal:Fluído espinal cerebral:Narrativo:
fr-FR French (France) Folate et tryptophane et métabolites Profil:Interprétation:Ponctuel:Liquide céphalorachidien:Résultat textuel:
it-IT Italian (Italy) Folato & Triptofano & Metaboliti, profilo:Imp:Pt:LCS:Nar:
Synonyms: Chimica Impressione/interpretazione di studio Liquido cerebrospinale Profilo di Folato & Triptofano e Metaboliti Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) folaat & tryptofaan & metabolieten patroon:interpretatie:moment:liquor cerebrospinalis:tekstueel:
Synonyms: foliumzuur; vitamine B11
tr-TR Turkish (Turkey) Folat ve triptofan ve metabolitleri örüntüsü:İzlnm:Zmlı:BOS:Öykü:
Synonyms: Folat ve triptofan ve metabolitleri paterni
zh-CN Chinese (China) 叶酸与色氨酸与代谢产物模式:印象:时间点:脑脊液:叙述型:
Synonyms: B 吲哚基丙氨酸;Beta 吲哚基丙氨酸;L-色氨酸;Trp;β吲哚基丙氨酸 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 Vit M;维生素 Bc;维生素 M;蝶酰谷氨酸 代谢产物 代谢废物 代谢废物类 代谢物 代谢物类 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 印象是一种诊断陈述,始终是对其他某种观察指标的解释或抽象(一系列检验项目结果、一幅图像或者整个某位病人),而且几乎总是由某位专业人员产生。;检查印象;检查印象/解释;检查的印象/解释;检查解释;解释;阐释 叙述;叙述性文字;报告;报告型;文字叙述;文本叙述型;文本描述;文本描述型 叶酸(Folic acid、Folate、维生素B9、维生素Bc、Vit M、维生素 M、蝶酰谷氨酸)与色氨酸(B 吲哚基丙氨酸、Beta 吲哚基丙氨酸、L-色氨酸、Trp、β吲哚基丙氨酸)相关吲哚(靛基质)与代谢产物(代谢物)模式(模式特征、特征模式、图谱、式样、组份、组分、成员) 时刻;随机;随意;瞬间 脊液 脊髓液 脑脊液(Cerebral spinal fluid,CSF) 脑脊髓液

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