Version 2.72

80204-1Influenza virus A and B identified in Nasopharynx by Shell vial cultureActive

Term Description

The nasopharyngeal specimen is obtained from a swab placed high in the nasopharynx.
Source: Regenstrief LOINC

Part Descriptions

LP36662-2   Influenza virus A & B
Influenza virus from the family Orthomyxoviridae are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C viruses are medically relevant to humans. Influenza A and B viruses have a similar structure whereby these viruses each contain eight discrete single-stranded RNA gene segments, each encoding at least one protein. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts including most often to domestic poultry but also to horses, swine, toothed whales and humans, among other species. Although influenza virus B has been isolated from seals, type B is isolated almost always from humans. Influenza C virus has been isolated from pigs and dogs. While influenza B and C virus also cause illness in humans, host switch events and high mutation rates among IAV types causes respiratory infections in humans ranging from asymptomatic to fatal and are the cause of the influenza pandemics in the 20th and 21st centuries. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. [PMID:25812763] [CDC:flu/about/viruses/types] Source: Regenstrief LOINC

LP36602-8   Shell vial culture
Virus culture is often more sensitive than trying to detect viruses directly in clinical samples. Shell vial culture is a modification of the conventional cell culture technique for rapid detection of viruses in vitro. The technique involves inoculation of the clinical specimen on to cell monolayer grown on a cover slip in a shell vial culture tube, followed by low speed centrifugation and incubation. This system works on the principle that the low speed centrifugation enhances viral infectivity to the susceptible cells. It is thought that the minor trauma to the cell surface produced as a result of low speed centrifugation mechanical force enhances the viral entry in to the cells, which in turn reduces the total time taken for the virus to produce infection of cells. Virus may be detected by direct fluorescent antibody (DFA) or indirect fluorescent antibody (IFA) staining within hours or days of inoculation. Source: Regenstrief LOINC

Fully-Specified Name

Influenza virus A & B identified
Shell vial culture

Additional Names

Short Name
FLUAV + FLUBV Nph Shell Vial Cult
Display Name
FLUAV and FLUBV identified Shell vial culture Nom (Nph)
Consumer Name Alpha
Influenza A and B culture, Nasopharynx

Example Answer List LL3796-1

Source: Diagnostic Hybrids

Answer Code Score Answer ID
No Influenza A virus, Influenza B virus, isolated in cell culture LA25510-1
Influenza A virus isolated in cell culture LA25511-9
Influenza B virus isolated in cell culture LA25512-7

Basic Attributes

First Released
Version 2.54
Last Updated
Version 2.56
Order vs. Observation

Member of these Groups

LG32757-3 Influenza virus

Language Variants Get Info

zh-CNChinese (China)
流感病毒 A 型与 B 型 已鉴定的:存在与否或特征标识:时间点:鼻咽:名义型:细胞培养瓶培养法
nl-NLDutch (Netherlands)
Influenzavirus A & B geïdentificeerd:identificator:moment:neusholte:nominaal:Shell vial'-kweek
fr-BEFrench (Belgium)
Virus de l'influenza A & B Identifiées:Présence ou identité:Temps ponctuel:Nasopharynx:Nominal:Culture sur lame en flacon
fr-CAFrench (Canada)
Virus de l'influenza A & B , Identifiés:Présence ou identité:Temps ponctuel:Nasopharynx:Nominal:Culture sur lame en flacon
fr-FRFrench (France)
Inosine triphosphate pyrophosphatase:Identification:Ponctuel:Nasopharynx:Résultat nominal:Culture fiole de coquille
it-ITItalian (Italy)
Influenza A & B, virus , identificato:Prid:Pt:Nph:Nom:Shell vial, coltura
es-MXSpanish (Mexico)
Virus de influenza A y B identificados:Presencia o identidad:Punto temporal:Nasofaringe:Nominal:Cultivo de viales de concha
es-ESSpanish (Spain)
Virus de la gripe A y B identificado:Presencia o identidad:Punto temporal:Nasofaringe:Nom:Cultivos en "shell vial"

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