80618-2
Zika virus IgM Ab [Units/volume] in Cerebral spinal fluid by Immunoassay
Active
Term Description
Quantitative analysis of Zika virus IgM antibodies in cerebral spinal fluid (CSF) specimens by immunoassay-based methods. Similar to most EIA tests, results are reported as a ratio of optical densities.
Zika virus IgM antibodies become detectable 4-8 days after the onset of symptoms and persist for months. Since IgM does not normally cross the blood-brain barrier, detection of Zika virus IgM in CSF implies CNS infection. Serological cross-reactivity is strong between Zika and other flaviviruses, especially Dengue virus. Therefore, positive results for this test are presumptive and should be confirmed by neutralizing antibody testing [LOINC: 80621-6]. Negative results for this test on a sample taken during the first week of illness does not rule out infection and the test should be repeated on a convalescent sample.
Source: Regenstrief LOINC
Part Description
LP200137-0 Zika virus
Zika virus (ZIKV) is a flavivirus transmitted primarily by the Aedes mosquito which was first identified in a sentinel monkey in the Zika forest in Uganda in 1947. Since 2014 it has spread explosively in the Americas where it has infected hundreds of thousands of people. About 80% of those infected are asymptomatic. Common symptoms include fever, headache, rash, arthralgia and conjunctivitis. Since the end of 2015, there has been an increase in ZIKV-associated cases of Guillain-Barre syndrome and a tremendous increase in cases of microcephaly in fetuses and newborns in Brazil, raising worldwide public health concern. Recent predictions are that the mosquito species A. Albopictus, which can hibernate and survive cool temperatures, will carry ZIKV to more temperate areas of North America, Australia and Southern Europe. It is still not clear whether ZIKV in humans increases viral titers enough to trigger a new cycle when an infected person is bitten by a naïve mosquito. Direct human-to-human transmission has been documented to occur perinatally, sexually (primarily through semen), through breastfeeding, blood transfusion and through occupational transmission in the laboratory setting. There are currently no specific anti-viral agents, vaccination or medical prophylaxis available. [PMID: 27148186]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Zika virus Ab.IgM
- Property
- ACnc
- Time
- Pt
- System
- CSF
- Scale
- Qn
- Method
- IA
Additional Names
- Short Name
- ZIKV IgM CSF IA-aCnc
- Display Name
- ZIKV IgM IA Qn (CSF)
- Consumer Name Alpha
- Zika virus IgM antibody, Spinal fluid
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.56
- Order vs. Observation
- Both
Member of these Groups
| LOINC Group | Group Name |
|---|---|
| LG32774-8 | Zika virus |
Language Variants
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 寨卡病毒 抗体.IgM: Synonyms: |
| es-ES | Spanish (Spain) | Virus Zika IgM: |
| it-IT | Italian (Italy) | Zika virus Ab.IgM: Synonyms: |
| fr-FR | French (France) | Zika virus Ac IgM: |
| tr-TR | Turkish (Turkey) | Zika virüs Ab.IgM: Synonyms: |
| nl-NL | Dutch (Netherlands) | zikavirus As.IgM: Synonyms: |
| de-DE | German (Germany) | Zika-Virus Ak.IgM: |
| es-MX | Spanish (Mexico) | Ab.IgM del virus del Zika: |
Example Units
| Unit | Source |
|---|---|
| {EIA_index} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR®
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=80618-2
LOINC Copyright
Copyright © 2023 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright