LOINC
Version 2.67

80685-1Clostridioides difficile toxin A+B tcdA+tcdB genes [Presence] in Stool by NAA with probe detectionActive

Term Description

Qualitative detection of nucleic acid sequences in the Clostridium difficile toxin A (tcdA) and B (tcdB) genes in stool specimens by real-time PCR methods. This assay does not differentiate between C. difficile toxin A and B genes. This term was created for, but not limited in use to, the submitter's test kit, xTAG® Gastrointestinal Pathogen Panel (GPP).
Source: Regenstrief LOINC

Part Description

LP204848-8   Clostridioides difficile toxin A+B tcdA+tcdB genes
Clostridium difficile toxin's A and B are encoded by the tcdA and tcdB genes, respectively. [PMID: 20664812] They share similar molecular characteristics with comparable sizes (308 kD for tcdA and 269 for tcdB) and 63% homology in their amino acid sequences. [PMID: 9312171] TcdA and tcdB are expressed in response to environmental stresses, such as antibiotics.[ PMID 15831824] Nucleic acid sequences within these genes are targeted to confirm the presence of C. difficile toxins and diagnose the cause of diarrhea, abdominal pain, fever, nausea and other toxin-producing symptoms. Source: Regenstrief LOINC

Fully-Specified Name

Component
Clostridioides difficile toxin A+B tcdA+tcdB genes
Property
PrThr
Time
Pt
System
Stool
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
C dif tox tcdA+tcdB Stl Ql NAA+probe
Display Name
C. difficile toxin A+B tcdA+tcdB genes NAA+probe Ql (Stl)

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.66
Change Reason
Removed parentheses around the gene names in the Component based on the current LOINC model; Updated genus name from Clostridium to Clostridioides based on current (2019) accepted nomenclature for this genus [PMID:27370902].
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
79381-0 Gastrointestinal pathogens panel - Stool by NAA with probe detection

Language Variants Get Info

zh-CNChinese (CHINA)
艰难梭菌毒素 A+B tcdA+tcdB 基因:存在情况或阈值:时间点:大便:序数型:探针法.基因扩增.靶向
nl-NLDutch (NETHERLANDS)
Clostridioides difficile toxine A+B (tcdA+tcdB) genen:aanwezigheid:moment:feces:ordinaal:moleculaire techniek (PCR)
fr-FRFrench (FRANCE)
Clostridium botulinum toxines A+B tcdA+tcdB gènes:Présence/Seuil:Ponctuel:Selles:Qualitatif:PCR amplification de cible
it-ITItalian (ITALY)
Clostridium Difficile (tcdA+tcdB), geni tossine A+B:PrThr:Pt:Feci:Ord:Sonda.amp.tar
es-ESSpanish (SPAIN)
Gen de la toxina del Clostridium difficile A+B (tcdA+tcdB):PrThr:Punto temporal:Heces:Ord:Sonda con amplificación dirigida

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80685-1