LOINC
Version 2.72

80825-3Zika virus envelope E gene [Presence] in Serum by NAA with probe detectionActive

Term Description

Per the Centers for Disease Control and Prevention's Trioplex Real-time RT-PCR Assay protocol, acceptable specimens for Zika testing are serum (not plasma), cerebrospinal fluid, urine, and amniotic fluid, and the probe target is the Zika virus envelope (E) gene.
Source: Regenstrief LOINC

Part Description

LP208630-6   Zika virus envelope (E) gene
Zika virus (ZIKV) is an arthropod-borne virus classified in the Flavivirus genus within the Falviviridae family 1. Flaviviruses include yellow fever virus, dengue virus, West Nile virus, St. Louis encephalitis virus and the Japanese encephalitis viruses. The genome of Flaviviruses is a single positive-strand RNA that is translated to produce a polyprotein that upon cleavage produces several proteins including the two major structural proteins (E and M). The "envelope E gene" and the "envelope M gene" correspond to the viral RNA regions that encode the E protein and the M protein. The virus envelope consists of a lipid bilayer derived from the host cell and 180 copies of M and E proteins arranged as 90 anti-parallel homodimers. N-linked glycosylation of the E protein may play a significant role in the pathogenicity of the virus. Further functional studies are needed to prove this hypothesis. [PMID:27148186] Source: Regenstrief LOINC

Fully-Specified Name

Component
Zika virus envelope (E) gene
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
Zika E gene Ser Ql NAA+probe
Display Name
ZIKV E gene NAA+probe Ql (S)
Consumer Name Alpha
Zika virus E gene, Blood

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.65
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
81154-7 Dengue and Chikungunya and Zika virus panel by NAA with probe detection

Member of these Groups

LG32774-8 Zika virus

Language Variants Get Info

zh-CNChinese (China)
寨卡病毒包膜 (E) 基因:存在情况或阈值:时间点:血清:序数型:探针法.基因扩增.靶向
nl-NLDutch (Netherlands)
zikavirus envelop (E) gen:aanwezigheid:moment:serum:ordinaal:moleculaire techniek (PCR)
fr-FRFrench (France)
Zika virus enveloppe gène E:Présence/Seuil:Ponctuel:Sérum:Qualitatif:PCR amplification de cible
it-ITItalian (Italy)
Zika virus, gene dell'involucro E:PrThr:Pt:Siero:Ord:Sonda.amp.tar
es-MXSpanish (Mexico)
Gen de la envoltura (E) del virus del Zika:Presencia o umbral:Punto temporal:Suero:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
es-ESSpanish (Spain)
Gen de la envoltura del virus Zika (E):PrThr:Punto temporal:Suero:Ord:Sonda con amplificación dirigida

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80825-3