80826-1Zika virus envelope E gene [Presence] in Cerebral spinal fluid by NAA with probe detectionActive
Term Description
Per the Centers for Disease Control and Prevention's Trioplex Real-time RT-PCR Assay protocol, acceptable specimens for Zika testing are serum (not plasma), cerebrospinal fluid, urine, and amniotic fluid, and the probe target is the Zika virus envelope (E) gene.
Source: Regenstrief LOINC
Part Description
LP208630-6 Zika virus envelope (E) gene
Zika virus (ZIKV) is an arthropod-borne virus classified in the Flavivirus genus within the Falviviridae family 1. Flaviviruses include yellow fever virus, dengue virus, West Nile virus, St. Louis encephalitis virus and the Japanese encephalitis viruses. The genome of Flaviviruses is a single positive-strand RNA that is translated to produce a polyprotein that upon cleavage produces several proteins including the two major structural proteins (E and M). The "envelope E gene" and the "envelope M gene" correspond to the viral RNA regions that encode the E protein and the M protein. The virus envelope consists of a lipid bilayer derived from the host cell and 180 copies of M and E proteins arranged as 90 anti-parallel homodimers. N-linked glycosylation of the E protein may play a significant role in the pathogenicity of the virus. Further functional studies are needed to prove this hypothesis. [PMID:27148186]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Zika virus envelope (E) gene
- Property
- PrThr
- Time
- Pt
- System
- CSF
- Scale
- Ord
- Method
- Probe.amp.tar
Additional Names
- Short Name
- Zika E gene CSF Ql NAA+probe
- Display Name
- ZIKV E gene NAA+probe Ql (CSF)
- Consumer Name Alpha
- Zika virus E gene, Spinal fluid
Example Answer List LL744-4
Source: Regenstrief Institute
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.65
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 81154-7 | Dengue and Chikungunya and Zika virus panel by NAA with probe detection |
Member of these Groups
| LG32774-8 | Zika virus |
Language Variants Get Info
- zh-CNChinese (China)
- 寨卡病毒包膜 (E) 基因:
存在情况或阈值: 时间点: 脑脊液: 序数型: 探针法.基因扩增.靶向 - nl-NLDutch (Netherlands)
- zikavirus envelop (E) gen:
aanwezigheid: moment: liquor cerebrospinalis: ordinaal: moleculaire techniek (PCR) - fr-FRFrench (France)
- Zika virus enveloppe gène E:
Présence/Seuil: Ponctuel: Liquide céphalorachidien: Qualitatif: PCR amplification de cible - it-ITItalian (Italy)
- Zika virus, gene dell'involucro E:
PrThr: Pt: LCS: Ord: Sonda.amp.tar - es-MXSpanish (Mexico)
- Gen de la envoltura (E) del virus del Zika:
Presencia o umbral: Punto temporal: Fluído espinal cerebral: Ordinal: Amplificación de ácidos nucleicos con detección de sonda - es-ESSpanish (Spain)
- Gen de la envoltura del virus Zika (E):
PrThr: Punto temporal: Líquido Cefalorraquideo: Ord: Sonda con amplificación dirigida
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80826-1
LOINC Copyright
Copyright © 2022 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright