Version 2.72

81116-6Hepatitis C virus core Ab+Ag [Presence] in SerumActive

Term Description

This assay detects hepatitis C core antigen and antibodies to the core antigen and does not distinguish between the two. The hepatitis C core protein forms the viral capsid. This term was created for, but is not limited in use to, the submitter's Biorad Monolisa HCV Ag-Ab ULTRA assay.
Source: Regenstrief LOINC

Part Description

LP207929-3   Hepatitis C virus core Ab+Ag
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books:NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

Fully-Specified Name

Hepatitis C virus core Ab+Ag

Additional Names

Short Name
HCV core Ab+Ag Ser Ql
Display Name
HCV core Ab+Ag Ql (S)
Consumer Name Alpha
Hepatitis C virus (HCV) Core Ab+Ag, Blood

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

First Released
Version 2.56
Last Updated
Version 2.56
Order vs. Observation

Member of these Groups

LG32754-0 Hepatitis C virus

Language Variants Get Info

zh-CNChinese (China)
nl-NLDutch (Netherlands)
Hepatitis C-virus core Ab + Ag:aanwezigheid:moment:serum:ordinaal:
fr-FRFrench (France)
Hépatite C virus core Ac+Ag:Présence/Seuil:Ponctuel:Sérum:Qualitatif:
it-ITItalian (Italy)
Epatite C virus, core Ab+Ag:PrThr:Pt:Siero:Ord:
pl-PLPolish (Poland)
wirus zapalenia wątroby typu C przeciwciała + antygen rdzeniowy:obecność lub wartość progowa:Punkt w czasie:Surowica:Porządkowy:
es-MXSpanish (Mexico)
Núcleo del virus de la hepatitis C Ab + Ag:Presencia o umbral:Punto temporal:Suero:Ordinal:
es-ESSpanish (Spain)
Anticuerpo + Antígeno core del vitus de la Hepatitis C:PrThr:Punto temporal:Suero:Ord:

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