LOINC
Version 2.67

81711-4Microsatellite instability marker panel - Cancer specimenActive

Part Description

LP212222-6   Microsatellite instability marker panel
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

Panel Hierarchy
Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
81711-4 Microsatellite instability marker panel - Cancer specimen
Indent81696-7 Microsatellite instability markers assessed [#] in Cancer specimen {#}
Indent81697-5 Microsatellite instability marker BAT25 in Cancer specimen Qualitative
Indent81698-3 Microsatellite instability marker BAT26 in Cancer specimen Qualitative
Indent81699-1 Microsatellite instability marker NR21 in Cancer specimen Qualitative
Indent81700-7 Microsatellite instability marker NR24 in Cancer specimen Qualitative
Indent81701-5 Microsatellite instability marker MONO27 in Cancer specimen Qualitative
Indent81702-3 Microsatellite instability marker D2S123 in Cancer specimen Qualitative
Indent81703-1 Microsatellite instability marker D5S346 in Cancer specimen Qualitative
Indent81704-9 Microsatellite instability marker D17S250 in Cancer specimen Qualitative
Indent81709-8 Microsatellite markers exhibiting instability [#] in Cancer specimen {#}
Indent81708-0 Microsatellite markers exhibiting instability/Microsatellite instability markers assessed in Cancer specimen %
Indent81695-9 Microsatellite instability [Interpretation] in Cancer specimen Qualitative

Fully-Specified Name

Component
Microsatellite instability marker panel
Property
-
Time
Pt
System
Cancer specimen
Scale
-
Method

Additional Names

Short Name
MSI mark Pnl Ca spec
Display Name
Microsatellite instability marker panel (Cancer specimen)

Basic Attributes

Class
PANEL.PATH
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.61
Change Reason
Updated System from "Tiss" to "Cancer.XXX" because MSI testing is performed on cancer specimens.; Updated System from "Cancer.XXX" to clarify that the test is performed on a cancer specimen.
Order vs. Observation
Order
Panel Type
Panel

Member of these Panels

LOINC Long Common Name
85905-8 Cancer pathology panel - Colorectal cancer specimen by CAP cancer protocols

Language Variants Get Info

zh-CNChinese (CHINA)
微卫星不稳定性标记组套:-:时间点:癌标本:-:
it-ITItalian (ITALY)
Marcatore di instabilità dei microsatelliti, panel:-:Pt:Campione tumore:-:
es-ESSpanish (SPAIN)
Panel de marcadores de inestabilidad de microsatélites:Propiedades mixtas (sólo paneles):Punto temporal:Muestra de cancer:-:

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=81711-4