LOINC
Version 2.67

81739-5Deprecated SCL-70 extractable nuclear Ab [Presence] in Cerebral spinal fluid by ImmunoblotDeprecated

Status Information

Status
Deprecated
Reason
Duplicate
Comment
Created with Method "IB" but upon further review found to be "IA", which makes this term a duplicate.
Map-To Long Common Name Mapping Guidance
63337-0 SCL-70 extractable nuclear Ab [Presence] in Cerebral spinal fluid by Immunoassay

Part Description

LP16758-2   SCL-70 extractable nuclear
Topoisomerase I (also known as Scl-70) is a nuclear enzyme that plays a role in releasing tension that is introduced in double-stranded DNA during DNA replication by transiently cleaving and rejoining one strand of the DNA duplex. Anti–Scl-70 autoantibodies are a marker of systemic sclerosis as well as other autoimmune diseases, including systemic lupus erythematosus (SLE). In patients with systemic sclerosis, anti-SCL-70 may be associated with more severe disease, and in patients with SLE, anti-SCL-70 suggests an increased risk of pulmonary hypertension and renal involvement. In general, anti-SCL-70 antibody status may help with diagnosis, treatment planning and prognosis in patients with connective tissue disease. [PMID: 11229469] Source: Regenstrief LOINC, PMID: 11229469

Fully-Specified Name

Component
SCL-70 extractable nuclear Ab
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
IB

Additional Names

Short Name
Deprecated ENA Scl70 Ab CSF Ql IB
Display Name
SCL-70 extractable nuclear Ab IB Ql (CSF)

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.58
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Groups

LG26773-8 SCL-70 extractable nuclear Ab|PrThr|Pt|CSF

Language Variants Get Info

zh-CNChinese (CHINA)
SCL-70 可提取性核 抗体:存在情况或阈值:时间点:脑脊液:序数型:免疫印迹法
nl-NLDutch (NETHERLANDS)
SCL-70 extraheerbare nucleaire As:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:immunoblotting
fr-BEFrench (BELGIUM)
SCL-70 nucléaire soluble Ac:PrThr:Temps ponctuel:LCR:Ordinal:Immunoblot
fr-CAFrench (CANADA)
SCL-70 nucléaire soluble , Ac:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Immunoblot
it-ITItalian (ITALY)
Nucleare estraibile SCL-70 , Ab:PrThr:Pt:LCS:Ord:IB
ru-RURussian (RUSSIAN FEDERATION)
SCL-70 экстрагируемый ядерный Ат:PrThr:ТчкВрм:ЦСЖ:Пор:ИБ
es-ESSpanish (SPAIN)
Antígeno nuclear extraíble SCL-70 Anticuerpos:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Inmunoblot (IB)
tr-TRTurkish (TURKEY)
SCL-70 özütlenebilir nükleer Ab:MevcEşik:Zmlı:BOS:Srl:IB

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=81739-5