82197-5Clostridioides difficile toxin A+B tcdA+tcdB genes [Presence] in Stool by NAA with non-probe detectionActive
Term Description
Qualitative detection of nucleic acid sequences in the Clostridium difficile toxin A (tcdA) and B (tcdB) genes in stool specimens by PCR and non-probe detection methods, such as melt curve analysis. This assay does not differentiate between C. difficile toxin A and B genes. This term was created for, but not limited in use to, the submitter's test kit, FilmArray Gastrointestinal Panel (GI) v2.1.
Source: Regenstrief LOINC
Part Description
LP204848-8 Clostridioides difficile toxin A+B tcdA+tcdB genes
Clostridium difficile toxin's A and B are encoded by the tcdA and tcdB genes, respectively.[PMID:20664812] They share similar molecular characteristics with comparable sizes (308 kD for tcdA and 269 for tcdB) and 63% homology in their amino acid sequences.[PMID:9312171] TcdA and tcdB are expressed in response to environmental stresses, such as antibiotics.[ PMID 15831824] Nucleic acid sequences within these genes are targeted to confirm the presence of C. difficile toxins and diagnose the cause of diarrhea, abdominal pain, fever, nausea and other toxin-producing symptoms.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Clostridioides difficile toxin A+B tcdA+tcdB genes
- Property
- PrThr
- Time
- Pt
- System
- Stool
- Scale
- Ord
- Method
- Non-probe.amp.tar
Additional Names
- Short Name
- C dif tox tcdA+tcdB Stl Ql NAA+non-probe
- Display Name
- C. difficile toxin A+B tcdA+tcdB genes NAA+non-probe Ql (Stl)
- Consumer Name Alpha
- Clostridioides difficile toxin A+B tcdA+tcdB genes, Stool
Example Answer List LL744-4
Source: Regenstrief Institute
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.66
- Change Reason
- Updated Component from "Clostridium difficile toxin A+B (tcdA+tcdB) genes" based on the current LOINC naming model for assays that detect specific bacteria and viral genes; Updated genus name from Clostridium to Clostridioides based on current (2019) accepted nomenclature for this genus [PMID:27370902].
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 82195-9 | Gastrointestinal pathogens DNA and RNA panel - Stool by NAA with non-probe detection |
Language Variants Get Info
- zh-CNChinese (China)
- 艰难梭菌毒素 A+B tcdA+tcdB 基因:
存在情况或阈值: 时间点: 大便: 序数型: 非探针法.基因扩增.靶向 - fr-FRFrench (France)
- Clostridioides difficime toxines A+B tcdA+tcdB gènes:
Présence/Seuil: Ponctuel: Selles: Qualitatif: Non-PCR amplification de cible - it-ITItalian (Italy)
- Clostridium Difficile (tcdA+tcdB), geni tossine A+B:
PrThr: Pt: Feci: Ord: Non-sonda.amp.tar - es-MXSpanish (Mexico)
- Toxina de Clostridioides difficile A + B genes tcdA + tcdB:
Presencia o umbral: Punto temporal: Heces: Ordinal: Amplificación de ácidos nucleicos con detección sin sonda - es-ESSpanish (Spain)
- Gen de la toxina del Clostridium difficile A+B (tcdA+tcdB):
PrThr: Punto temporal: Heces: Ord: Amplificación del objetivo no basado en sonda
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=82197-5
LOINC Copyright
Copyright © 2022 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright