Version 2.72

82197-5Clostridioides difficile toxin A+B tcdA+tcdB genes [Presence] in Stool by NAA with non-probe detectionActive

Term Description

Qualitative detection of nucleic acid sequences in the Clostridium difficile toxin A (tcdA) and B (tcdB) genes in stool specimens by PCR and non-probe detection methods, such as melt curve analysis. This assay does not differentiate between C. difficile toxin A and B genes. This term was created for, but not limited in use to, the submitter's test kit, FilmArray Gastrointestinal Panel (GI) v2.1.
Source: Regenstrief LOINC

Part Description

LP204848-8   Clostridioides difficile toxin A+B tcdA+tcdB genes
Clostridium difficile toxin's A and B are encoded by the tcdA and tcdB genes, respectively.[PMID:20664812] They share similar molecular characteristics with comparable sizes (308 kD for tcdA and 269 for tcdB) and 63% homology in their amino acid sequences.[PMID:9312171] TcdA and tcdB are expressed in response to environmental stresses, such as antibiotics.[ PMID 15831824] Nucleic acid sequences within these genes are targeted to confirm the presence of C. difficile toxins and diagnose the cause of diarrhea, abdominal pain, fever, nausea and other toxin-producing symptoms. Source: Regenstrief LOINC

Fully-Specified Name

Clostridioides difficile toxin A+B tcdA+tcdB genes

Additional Names

Short Name
C dif tox tcdA+tcdB Stl Ql NAA+non-probe
Display Name
C. difficile toxin A+B tcdA+tcdB genes NAA+non-probe Ql (Stl)
Consumer Name Alpha
Clostridioides difficile toxin A+B tcdA+tcdB genes, Stool

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

First Released
Version 2.56
Last Updated
Version 2.66
Change Reason
Updated Component from "Clostridium difficile toxin A+B (tcdA+tcdB) genes" based on the current LOINC naming model for assays that detect specific bacteria and viral genes; Updated genus name from Clostridium to Clostridioides based on current (2019) accepted nomenclature for this genus [PMID:27370902].
Order vs. Observation

Member of these Panels

LOINC Long Common Name
82195-9 Gastrointestinal pathogens DNA and RNA panel - Stool by NAA with non-probe detection

Language Variants Get Info

zh-CNChinese (China)
艰难梭菌毒素 A+B tcdA+tcdB 基因:存在情况或阈值:时间点:大便:序数型:非探针法.基因扩增.靶向
fr-FRFrench (France)
Clostridioides difficime toxines A+B tcdA+tcdB gènes:Présence/Seuil:Ponctuel:Selles:Qualitatif:Non-PCR amplification de cible
it-ITItalian (Italy)
Clostridium Difficile (tcdA+tcdB), geni tossine A+B:PrThr:Pt:Feci:Ord:Non-sonda.amp.tar
es-MXSpanish (Mexico)
Toxina de Clostridioides difficile A + B genes tcdA + tcdB:Presencia o umbral:Punto temporal:Heces:Ordinal:Amplificación de ácidos nucleicos con detección sin sonda
es-ESSpanish (Spain)
Gen de la toxina del Clostridium difficile A+B (tcdA+tcdB):PrThr:Punto temporal:Heces:Ord:Amplificación del objetivo no basado en sonda

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