Version 2.72

82212-2Rotavirus A RNA [Presence] in Stool by NAA with non-probe detectionActive

Term Description

Qualitative detection of nucleic acid sequences in the Rotavirus A RNA in stool specimens by PCR and non-probe detection methods, such as melt curve analysis. This term was created for, but not limited in use to, the submitter's test kit, FilmArray Gastrointestinal Panel (GI) v2.1.
Source: Regenstrief LOINC

Part Description

LP204843-9   Rotavirus A
Rotaviruses are non-enveloped, multilayered, icosahedral viruses composed of an outer layer, an inner layer, and a core. After the immature, double-layered virus is assembled in the host cell cytoplasm, they bud across the endoplasmic reticulum (ER) and acquire a temporary membrane that has on its surface the ER resident viral glycoproteins NSP4, VP4 and VP7. The virus loses its temporary membrane and the NSP4 glycoprotein as it moves toward the center of the ER cisternae. The VP4 and VP7 proteins are pushed to the outermost membrane layer and become the mature triple-layered rotavirus. The outer capsid glycoprotein VP7 is believed to be important for the attachment to and entry in the host cell. After it enters the host cell, the VP7 glycoprotein is lost. [UniProt:Q89865] When the host cell lyses, the mature virus are released. There are eight groups of rotavirus, A through H. Groups A, B, C, and H are associated with an acute gastroenteritis and are found in humans and animals. Groups D, E, F, and G are found only in animals. Rotavirus A (RVA) are the cause an acute gastroenteritis in children and animals. RVA is the most common infectious organism to cause severe gastroenteritis in children less than 3 years of age. It is estimated that 95% of children worldwide between the ages of 3 and 5 will become infected with RVA. Approximately 8000 children under 5 years of age in Latin America and the Caribbean die of acute enteritis caused by RVA. [PMID:2556635][http://www.sciencedirect.com/science/article/pii/S004268220700400X?via%3Dihub][PMID:27462899] Source: Regenstrief LOINC, A blood group

Fully-Specified Name

Rotavirus A RNA

Additional Names

Short Name
RVA RNA Stl Ql NAA+non-probe
Display Name
Rotavirus A RNA NAA+non-probe Ql (Stl)
Consumer Name Alpha
Rotavirus A, Stool

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

First Released
Version 2.56
Last Updated
Version 2.64
Change Reason
Abbreviated "Rotavirus A" to "RVA" in the Shortname for consistency across terms.
Order vs. Observation

Member of these Panels

LOINC Long Common Name
82195-9 Gastrointestinal pathogens DNA and RNA panel - Stool by NAA with non-probe detection

Language Variants Get Info

zh-CNChinese (China)
轮状病毒 A 组 RNA:存在情况或阈值:时间点:大便:序数型:非探针法.基因扩增.靶向
fr-FRFrench (France)
Rotavirus A ARN:Présence/Seuil:Ponctuel:Selles:Qualitatif:Non-PCR amplification de cible
it-ITItalian (Italy)
Rotavirus A RNA:PrThr:Pt:Feci:Ord:Non-sonda.amp.tar
es-MXSpanish (Mexico)
ARN del rotavirus A:Presencia o umbral:Punto temporal:Heces:Ordinal:Amplificación de ácidos nucleicos con detección sin sonda
es-ESSpanish (Spain)
Rotavirus A RNA:PrThr:Punto temporal:Heces:Ord:Amplificación del objetivo no basado en sonda

LOINC FHIR® API Example - CodeSystem Request Get Info