82212-2Rotavirus A RNA [Presence] in Stool by NAA with non-probe detectionActive
Term Description
Qualitative detection of nucleic acid sequences in the Rotavirus A RNA in stool specimens by PCR and non-probe detection methods, such as melt curve analysis. This term was created for, but not limited in use to, the submitter's test kit, FilmArray Gastrointestinal Panel (GI) v2.1.
Source: Regenstrief LOINC
Part Description
LP204843-9 Rotavirus A
Rotaviruses are non-enveloped, multilayered, icosahedral viruses composed of an outer layer, an inner layer, and a core. After the immature, double-layered virus is assembled in the host cell cytoplasm, they bud across the endoplasmic reticulum (ER) and acquire a temporary membrane that has on its surface the ER resident viral glycoproteins NSP4, VP4 and VP7. The virus loses its temporary membrane and the NSP4 glycoprotein as it moves toward the center of the ER cisternae. The VP4 and VP7 proteins are pushed to the outermost membrane layer and become the mature triple-layered rotavirus. The outer capsid glycoprotein VP7 is believed to be important for the attachment to and entry in the host cell. After it enters the host cell, the VP7 glycoprotein is lost. [UniProt:Q89865] When the host cell lyses, the mature virus are released. There are eight groups of rotavirus, A through H. Groups A, B, C, and H are associated with an acute gastroenteritis and are found in humans and animals. Groups D, E, F, and G are found only in animals. Rotavirus A (RVA) are the cause an acute gastroenteritis in children and animals. RVA is the most common infectious organism to cause severe gastroenteritis in children less than 3 years of age. It is estimated that 95% of children worldwide between the ages of 3 and 5 will become infected with RVA. Approximately 8000 children under 5 years of age in Latin America and the Caribbean die of acute enteritis caused by RVA. [PMID:2556635][http://www.sciencedirect.com/science/article/pii/S004268220700400X?via%3Dihub][PMID:27462899]
Source: Regenstrief LOINC, A blood group
Fully-Specified Name
- Component
- Rotavirus A RNA
- Property
- PrThr
- Time
- Pt
- System
- Stool
- Scale
- Ord
- Method
- Non-probe.amp.tar
Additional Names
- Short Name
- RVA RNA Stl Ql NAA+non-probe
- Display Name
- Rotavirus A RNA NAA+non-probe Ql (Stl)
- Consumer Name Alpha
- Rotavirus A, Stool
Example Answer List LL744-4
Source: Regenstrief Institute
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.56
- Last Updated
- Version 2.64
- Change Reason
- Abbreviated "Rotavirus A" to "RVA" in the Shortname for consistency across terms.
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 82195-9 | Gastrointestinal pathogens DNA and RNA panel - Stool by NAA with non-probe detection |
Language Variants Get Info
- zh-CNChinese (China)
- 轮状病毒 A 组 RNA:
存在情况或阈值: 时间点: 大便: 序数型: 非探针法.基因扩增.靶向 - fr-FRFrench (France)
- Rotavirus A ARN:
Présence/Seuil: Ponctuel: Selles: Qualitatif: Non-PCR amplification de cible - it-ITItalian (Italy)
- Rotavirus A RNA:
PrThr: Pt: Feci: Ord: Non-sonda.amp.tar - es-MXSpanish (Mexico)
- ARN del rotavirus A:
Presencia o umbral: Punto temporal: Heces: Ordinal: Amplificación de ácidos nucleicos con detección sin sonda - es-ESSpanish (Spain)
- Rotavirus A RNA:
PrThr: Punto temporal: Heces: Ord: Amplificación del objetivo no basado en sonda
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=82212-2
LOINC Copyright
Copyright © 2022 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright