LOINC
Version 2.67

82416-9Deprecated Histone Ab [Presence] in Cerebral spinal fluid by ImmunoblotDeprecated

Status Information

Status
Deprecated
Reason
Duplicate
Comment
Created with Method "IB" but upon further review found to be "IA", which makes this term a duplicate.
Map-To Long Common Name Mapping Guidance
63264-6 Histone Ab [Presence] in Cerebral spinal fluid by Immunoassay

Part Description

LP16714-5   Histone
Histones are small nuclear proteins that together with dsDNA, represent a nucleosome, the structural unit of chromatin. Anti-histone antibodies are associated with various autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis, Sjogren's syndrome, systemic sclerosis, infectious diseases (including HIV), and some neurological disorders such as Alzheimer's disease and dementia. Nearly all patients with drug-induced SLE have anti-histone antibodies, but they are also present in patients with idiopathic forms of the disease. One study showed a correlation between SLE with positive anti-dsDNA, anti-nucleosome and anti-histone antibodies and renal disease, including proliferative glomerulonephritis. [PMID: 24649358] Source: Regenstrief LOINC, PMID: 24649358

Fully-Specified Name

Component
Histone Ab
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
IB

Additional Names

Short Name
Deprecated Histone Ab CSF Ql IB
Display Name
Histone Ab IB Ql (CSF)

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.58
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Groups

LG26116-0 Histone Ab|PrThr|Pt|CSF

Language Variants Get Info

zh-CNChinese (CHINA)
组蛋白 抗体:存在情况或阈值:时间点:脑脊液:序数型:免疫印迹法
nl-NLDutch (NETHERLANDS)
histon As:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:immunoblotting
et-EEEstonian (ESTONIA)
Histoon antikehad:PrThr:Pt:CSF:Ord:IB
fr-BEFrench (BELGIUM)
Histone Ac:PrThr:Temps ponctuel:LCR:Ordinal:Immunoblot
fr-CAFrench (CANADA)
Histone , Ac:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Immunoblot
it-ITItalian (ITALY)
Istone , Ab:PrThr:Pt:LCS:Ord:IB
ru-RURussian (RUSSIAN FEDERATION)
Гистон Ат:PrThr:ТчкВрм:ЦСЖ:Пор:ИБ
es-ESSpanish (SPAIN)
Histona Anticuerpos:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Inmunoblot (IB)
tr-TRTurkish (TURKEY)
Histon Ab:MevcEşik:Zmlı:BOS:Srl:IB

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=82416-9