LOINC
Version 2.67

82429-2Deprecated Nucleosome Ab [Presence] in Serum by ImmunoblotDeprecated

Status Information

Status
Deprecated
Reason
Duplicate
Comment
Created with Method "IB" but upon further review found to be "IA", which makes this term a duplicate.
Map-To Long Common Name Mapping Guidance
63300-8 Nucleosome Ab [Presence] in Serum by Immunoassay

Part Description

LP31804-5   Nucleosome
The nucleosome is the structural unit of chromatin and consists of a segment of dsDNA coiled around a histone core. Anti-chromatin autoantibodies, such as those found in patients with systemic lupus erythematosus (SLE) fall in to two categories: those directed against individual components of chromatin, such as DNA and histone, and those directed against the intact nucleosome. Traditionally anti-dsDNA antibodies have been among the ones used for diagnosis and monitoring of SLE, however, studies have shown that for some patients, the nucleosome is the primary antigen in SLE, and anti-nucleosome antibodies may provide a better reflection of disease activity. A subset of patients who are positive for anti-nucleosome antibodies but negative for anti-dsDNA antibodies may have a milder course of SLE that does not involve the kidneys. [PMID: 25193804] Source: Regenstrief LOINC, PMID: 25193804

Fully-Specified Name

Component
Nucleosome Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IB

Additional Names

Short Name
Deprecated Nucleosome Ab Ser Ql IB
Display Name
Nucleosome Ab IB Ql (S)

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.58
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Groups

LG21386-4 Nucleosome Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (CHINA)
核小体 抗体:存在情况或阈值:时间点:血清:序数型:免疫印迹法
nl-NLDutch (NETHERLANDS)
nucleosoom As:aanwezigheid:moment:serum:ordinaal:immunoblotting
et-EEEstonian (ESTONIA)
Nukleosoom antikehad:PrThr:Pt:S:Ord:IB
fr-BEFrench (BELGIUM)
Nucléosome Ac:PrThr:Temps ponctuel:Sérum:Ordinal:Immunoblot
fr-CAFrench (CANADA)
Nucléosome , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoblot
it-ITItalian (ITALY)
Nucleosoma , Ab:PrThr:Pt:Siero:Ord:IB
ru-RURussian (RUSSIAN FEDERATION)
Нуклеосома Ат:PrThr:ТчкВрм:Сыв:Пор:ИБ
es-ESSpanish (SPAIN)
Nucleosoma Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunoblot (IB)
tr-TRTurkish (TURKEY)
Nükleozom Ab:MevcEşik:Zmlı:Ser:Srl:IB

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=82429-2