LOINC
Version 2.67

82456-5Human papilloma virus 16 E6+E7 mRNA [Presence] in Cervix by NAA with probe detectionActive

Term Description

Detects E6/E7 viral messenger RNA (mRNA) of human papillomavirus (HPV) types 16 in cervical specimens from women with positive HPV screening assay results. This term was created for, but not limited in use to, the Aptima HPV 16 18/45 genotype assay.To report results for HPV 18/45 use Human papilloma virus 18+45 E6+E7 mRNA [Presence] in Cervix by Probe and signal amplification method [LOINC: 75694-0].
Source: Regenstrief LOINC

Part Description

LP221166-4   Human papilloma virus 16 E6+E7 mRNA
Human papilloma virus (HPV) is a double-stranded DNA virus that includes 120 types that infect cutaneous and mucosal epithelial cells. The HPV that infect the cervix are categorized as low or high risk depending upon their carcinogenicity. High risk HPV types can lead to low-grade cervical cell abnormalities, pre-cancerous cellular abnormalities and anogenital cancer. Type 16 is a high risk HPV and is implicated in roughly 50% of cervical cancers around the world. E6/E7 genes in cervical tumors interfere with the control of cell proliferation and cell division and can be used for targeted anti-cancer therapy. [PMID: 9448307] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, Human papilloma virus (Wikipedia)

Fully-Specified Name

Component
Human papilloma virus 16 E6+E7 mRNA
Property
PrThr
Time
Pt
System
Cvx
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
HPV 16 E6+E7 mRNA Cvx Ql NAA+probe
Display Name
HPV 16 E6+E7 mRNA NAA+probe Ql (Cvx)

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.63
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
90766-7 HEDIS 2019 Value Sets
94137-7 HEDIS 2020 Value Sets
82457-3 Human papilloma virus 16 and 18+45 E6+E7 mRNA panel - Cervix by NAA with probe detection

Language Variants Get Info

zh-CNChinese (CHINA)
人乳头瘤病毒 16 E6+E7 mRNA:存在情况或阈值:时间点:子宫颈:序数型:探针法.基因扩增.靶向
nl-NLDutch (NETHERLANDS)
Humaan papilloma virus 16 E6+E7 mRNA:aanwezigheid:moment:cervix:ordinaal:moleculaire techniek (PCR)
fr-FRFrench (FRANCE)
Papillomavirus humain 16 ARNm E6+E7:Présence/Seuil:Ponctuel:Col de l'utérus:Qualitatif:PCR amplification de cible
it-ITItalian (ITALY)
Papilloma virus umano 16 E6+E7 mRNA:PrThr:Pt:Cvx:Ord:Sonda.amp.tar
es-ESSpanish (SPAIN)
mRNA del virus 16E6+E7 del papiloma humano:PrThr:Punto temporal:Cuello uterino:Ord:Sonda con amplificación dirigida

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=82456-5