LOINC
Version 2.72

82857-4Tetrahydrocortisol+allo-tetrahydrocortisol/Tetrahydrocortisone [Molar ratio] in 24 hour UrineActive

Term Description

The quantitative ratios of various steroids in urine are measured to diagnose conditions such as 17-alpha-, 21-, and 11-beta hydroxylase deficiencies, pseudohypoaldosteronismus, 3-beta hydroxysteroid dehydrogenase deficiency, corticosterone methyl oxidase deficiency, 11-beta hydroxysteroid dehydrogenase types 1 and 2 deficiency, and 5-alpha reductase deficiency. The results along with clinical symptoms and past medical history are used for the assessment and treatment of the associated deficiency or condition. Below are examples of various disorders and their associated urinary findings:
1. 17-alpha hydroxylase deficiency: (THA+THB+5aTHB)/(THE+THF+5aTHF) > 10, (THA+THB+5aTHB)/(AN+ET) > 10.
2. 21-hydroxylase deficiency: 17HP/(THE+THF+5aTHF) > 0.25, PT/(THE+THF+5aTHF) > 0.25.
3. 11-beta HSD2 deficiency: (THF+5aTHF)/THE > 3
4. 11-beta HSD1 deficiency: (THF+5aTHF)/THE < 0.1
5. 11-beta hydroxylase deficiency: 100*THS/(THE+THF+5aTHF) > 10, 100*THDOC/(THE+THF+5aTHF) > 10
6. Pseudohypoaldosteronismus: 100*THALDO/(THE+THF+5aTHF) > 5
7. 5-alpha reductase: ET/AN > 5, THF/5aTHF > 10
Where AN = Androsterone, ET= etiocholanolone, 17HP= metabolites of 17-OH-progesterone (pregnandiol, pregnantriol, 17-OH-pregnanolone), THA = tetrahydro compound A, THB = tetrahydrocorticosterone, 5aTHB =5 alpha tetrahydrocorticosterone, THE = tetrahydrocortisone, THF = Tetrahydrocortisone, 5aTHF = 5a-tetrahydrocortisone or Allo-tetrahydrocortisone, THS = tetrahydrodeoxycortisol, THALDO = tetrahydroaldosterone, and THDOC =tetrahydrodeoxycortisone
[NLM Catalog ID:101631718]
Source: Regenstrief LOINC

Fully-Specified Name

Component
Tetrahydrocortisol+allo-tetrahydrocortisol/Tetrahydrocortisone
Property
SRto
Time
24H
System
Urine
Scale
Qn
Method

Additional Names

Short Name
THF+Allo-THF/THE 24h Ur-sRto
Display Name
Tetrahydrocortisol+allo-tetrahydrocortisol/Tetrahydrocortisone (24H U) [Molar ratio]
Consumer Name Alpha
Tetrahydrocortisol+allo-tetrahydrocortisol/Tetrahydrocortisone, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.58
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
73885-6 Steroid fractions panel - 24 hour Urine

Member of these Groups

LG37435-1 Tetrahydrocortisol+allo-tetrahydrocortisol/Tetrahydrocortisone|SRto|Urine

Language Variants Get Info

zh-CNChinese (China)
四氢皮质醇+别-四氢皮质醇/四氢可的松:物质的量比率:24小时:尿液:定量型:
nl-NLDutch (Netherlands)
tetrahydrocortisol + allo-tetrahydrocortisol/tetrahydrocortison:molaire verhouding:24 uur:urine:kwantitatief:
fr-FRFrench (France)
Tetrahydrocortisol+allo-tétrahydrocortisol/tétrahydrocortisone:Moles ratio:24H:Urine:Numérique:
it-ITItalian (Italy)
Tetraidrocortisolo+allo-tetraidrocortisolo/Tetraidrocortisone:Srto:24h:Urine:Qn:
es-MXSpanish (Mexico)
Tetrahidrocortisol + alo-tetrahidrocortisol / tetrahidrocortisona:Proporción de sustancia:24H:Orina:Cuantitativo:
es-ESSpanish (Spain)
Tetrahidrocortisol+alo-tetrahidrocortisol/Tetrahidrocortisona:Relacion de Sustancia:24 horas:Orina:Qn:

Example Units

Unit Source
{ratio} Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=82857-4