82861-6
11-Deoxytetrahydrocortisol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol [Molar ratio] in 24 hour Urine
Active
Term Description
The quantitative ratios of various steroids in urine are measured to diagnose conditions such as 17-alpha-, 21-, and 11-beta hydroxylase deficiencies, pseudohypoaldosteronismus, 3-beta hydroxysteroid dehydrogenase deficiency, corticosterone methyl oxidase deficiency, 11-beta hydroxysteroid dehydrogenase types 1 and 2 deficiency, and 5-alpha reductase deficiency. The results along with clinical symptoms and past medical history are used for the assessment and treatment of the associated deficiency or condition. Below are examples of various disorders and their associated urinary findings:
1. 17-alpha hydroxylase deficiency: (THA+THB+5aTHB)/(THE+THF+5aTHF) > 10, (THA+THB+5aTHB)/(AN+ET) > 10.
2. 21-hydroxylase deficiency: 17HP/(THE+THF+5aTHF) > 0.25, PT/(THE+THF+5aTHF) > 0.25.
3. 11-beta HSD2 deficiency: (THF+5aTHF)/THE > 3
4. 11-beta HSD1 deficiency: (THF+5aTHF)/THE < 0.1
5. 11-beta hydroxylase deficiency: 100*THS/(THE+THF+5aTHF) > 10, 100*THDOC/(THE+THF+5aTHF) > 10
6. Pseudohypoaldosteronismus: 100*THALDO/(THE+THF+5aTHF) > 5
7. 5-alpha reductase: ET/AN > 5, THF/5aTHF > 10
Where AN = Androsterone, ET= etiocholanolone, 17HP= metabolites of 17-OH-progesterone (pregnandiol, pregnantriol, 17-OH-pregnanolone), THA = tetrahydro compound A, THB = tetrahydrocorticosterone, 5aTHB =5 alpha tetrahydrocorticosterone, THE = tetrahydrocortisone, THF = Tetrahydrocortisone, 5aTHF = 5a-tetrahydrocortisone or Allo-tetrahydrocortisone, THS = tetrahydrodeoxycortisol, THALDO = tetrahydroaldosterone, and THDOC =tetrahydrodeoxycortisone
[NLM Catalog ID: 101631718]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- 11-Deoxytetrahydrocortisol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol
- Property
- SRto
- Time
- 24H
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- THS/THE+THF+5a-THF 24h Ur-sRto
- Display Name
- 11-Deoxytetrahydrocortisol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol (24H U) [Molar ratio]
- Consumer Name Alpha Get Info
- 11-Deoxytetrahydrocortisol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha Tetrahydrocortisol, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.58
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
73885-6 | Steroid fractions panel - 24 hour Urine |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG37438-5 | 11-Deoxytetrahydrocortisol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | 11-Deoxitetrahidrocortisol/Tetrahidrocortisona+tetrahidrocortisol+5-alfa-tetrahidrocortisol: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | 11-desoxitetrahidrocortisol / tetrahidrocortisona + tetrahidrocortisol + 5-alfa tetrahidrocortisol: |
fr-FR | French (France) | 11-déoxytétrahydrocortisol/tétrahydrocortisone+tétrahydrocortisol+5-alpha tétrahydrocortisol: |
it-IT | Italian (Italy) | 11-Deossitetraidrocortisolo/Tetraidrocortisone+tetraidrocortisolo+5-alfa tetraidrocortisolo: Synonyms: 24 Ore Chimica Rapporto di sostanza |
nl-NL | Dutch (Netherlands) | 11-deoxytetrahydrocortisol/tetrahydrocortison + tetrahydrocortisol + 5-alfa tetrahydrocortisol: Synonyms: 24U |
zh-CN | Chinese (China) | 11-脱氧四氢皮质醇/四氢可的松+四氢皮质醇+5-alpha 四氢皮质醇: Synonyms: 11-脱氧四氢皮质醇(THC、 |
Example Units
Unit | Source |
---|---|
{ratio} | Example UCUM Units |
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