LOINC
Version 2.72

82862-411-Deoxytetrahydrocortisol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol [Molar ratio] in UrineActive

Term Description

The quantitative ratios of various steroids in urine are measured to diagnose conditions such as 17-alpha-, 21-, and 11-beta hydroxylase deficiencies, pseudohypoaldosteronismus, 3-beta hydroxysteroid dehydrogenase deficiency, corticosterone methyl oxidase deficiency, 11-beta hydroxysteroid dehydrogenase types 1 and 2 deficiency, and 5-alpha reductase deficiency. The results along with clinical symptoms and past medical history are used for the assessment and treatment of the associated deficiency or condition. Below are examples of various disorders and their associated urinary findings:
1. 17-alpha hydroxylase deficiency: (THA+THB+5aTHB)/(THE+THF+5aTHF) > 10, (THA+THB+5aTHB)/(AN+ET) > 10.
2. 21-hydroxylase deficiency: 17HP/(THE+THF+5aTHF) > 0.25, PT/(THE+THF+5aTHF) > 0.25.
3. 11-beta HSD2 deficiency: (THF+5aTHF)/THE > 3
4. 11-beta HSD1 deficiency: (THF+5aTHF)/THE < 0.1
5. 11-beta hydroxylase deficiency: 100*THS/(THE+THF+5aTHF) > 10, 100*THDOC/(THE+THF+5aTHF) > 10
6. Pseudohypoaldosteronismus: 100*THALDO/(THE+THF+5aTHF) > 5
7. 5-alpha reductase: ET/AN > 5, THF/5aTHF > 10
Where AN = Androsterone, ET= etiocholanolone, 17HP= metabolites of 17-OH-progesterone (pregnandiol, pregnantriol, 17-OH-pregnanolone), THA = tetrahydro compound A, THB = tetrahydrocorticosterone, 5aTHB =5 alpha tetrahydrocorticosterone, THE = tetrahydrocortisone, THF = Tetrahydrocortisone, 5aTHF = 5a-tetrahydrocortisone or Allo-tetrahydrocortisone, THS = tetrahydrodeoxycortisol, THALDO = tetrahydroaldosterone, and THDOC =tetrahydrodeoxycortisone
[NLM Catalog ID:101631718]
Source: Regenstrief LOINC

Fully-Specified Name

Component
11-Deoxytetrahydrocortisol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol
Property
SRto
Time
Pt
System
Urine
Scale
Qn
Method

Additional Names

Short Name
THS/THE+THF+5a-THF Ur-sRto
Display Name
11-Deoxytetrahydrocortisol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol (U) [Molar ratio]
Consumer Name Alpha
11-Deoxytetrahydrocortisol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha Tetrahydrocortisol, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.58
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
73886-4 Steroid fractions panel - Urine

Member of these Groups

LG37438-5 11-Deoxytetrahydrocortisol/Tetrahydrocortisone+tetrahydrocortisol+5-alpha tetrahydrocortisol|SRto|Urine

Language Variants Get Info

zh-CNChinese (China)
11-脱氧四氢皮质醇/四氢可的松+四氢皮质醇+5-alpha 四氢皮质醇:物质的量比率:时间点:尿液:定量型:
nl-NLDutch (Netherlands)
11-deoxytetrahydrocortisol/tetrahydrocortison + tetrahydrocortisol + 5-alfa tetrahydrocortisol:molaire verhouding:moment:urine:kwantitatief:
fr-FRFrench (France)
11-déoxytétrahydrocortisol/tétrahydrocortisone+tétrahydrocortisol+5-alpha tétrahydrocortisol:Moles ratio:Ponctuel:Urine:Numérique:
it-ITItalian (Italy)
11-Deossitetraidrocortisolo/Tetraidrocortisone+tetraidrocortisolo+5-alfa tetraidrocortisolo:Srto:Pt:Urine:Qn:
es-MXSpanish (Mexico)
11-desoxitetrahidrocortisol / tetrahidrocortisona + tetrahidrocortisol + 5-alfa tetrahidrocortisol:Proporción de sustancia:Punto temporal:Orina:Cuantitativo:
es-ESSpanish (Spain)
11-Deoxitetrahidrocortisol/Tetrahidrocortisona+tetrahidrocortisol+5-alfa-tetrahidrocortisol:Relacion de Sustancia:Punto temporal:Orina:Qn:

Example Units

Unit Source
{ratio} Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=82862-4