LOINC
Version 2.73

82881-4Etiocholanolone/Androsterone [Molar ratio] in UrineActive

Term Description

The quantitative ratios of various steroids in urine are measured to diagnose conditions such as 17-alpha-, 21-, and 11-beta hydroxylase deficiencies, pseudohypoaldosteronismus, 3-beta hydroxysteroid dehydrogenase deficiency, corticosterone methyl oxidase deficiency, 11-beta hydroxysteroid dehydrogenase types 1 and 2 deficiency, and 5-alpha reductase deficiency. The results along with clinical symptoms and past medical history are used for the assessment and treatment of the associated deficiency or condition. Below are examples of various disorders and their associated urinary findings:
1. 17-alpha hydroxylase deficiency: (THA+THB+5aTHB)/(THE+THF+5aTHF) > 10, (THA+THB+5aTHB)/(AN+ET) > 10.
2. 21-hydroxylase deficiency: 17HP/(THE+THF+5aTHF) > 0.25, PT/(THE+THF+5aTHF) > 0.25.
3. 11-beta HSD2 deficiency: (THF+5aTHF)/THE > 3
4. 11-beta HSD1 deficiency: (THF+5aTHF)/THE < 0.1
5. 11-beta hydroxylase deficiency: 100*THS/(THE+THF+5aTHF) > 10, 100*THDOC/(THE+THF+5aTHF) > 10
6. Pseudohypoaldosteronismus: 100*THALDO/(THE+THF+5aTHF) > 5
7. 5-alpha reductase: ET/AN > 5, THF/5aTHF > 10
Where AN = Androsterone, ET= etiocholanolone, 17HP= metabolites of 17-OH-progesterone (pregnandiol, pregnantriol, 17-OH-pregnanolone), THA = tetrahydro compound A, THB = tetrahydrocorticosterone, 5aTHB =5 alpha tetrahydrocorticosterone, THE = tetrahydrocortisone, THF = Tetrahydrocortisone, 5aTHF = 5a-tetrahydrocortisone or Allo-tetrahydrocortisone, THS = tetrahydrodeoxycortisol, THALDO = tetrahydroaldosterone, and THDOC =tetrahydrodeoxycortisone
[NLM Catalog ID:101631718]
Source: Regenstrief LOINC

Part Descriptions

LP15564-5   Etiocholanolone
The 5-beta-reduced isomer of ANDROSTERONE. Etiocholanolone is a major metabolite of TESTOSTERONE and ANDROSTENEDIONE in many mammalian species including humans. It is excreted in the URINE. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: National Library of Medicine, MeSH 2006, Androsterone (Wikipedia)

LP15564-5   Etiocholanolone
Etiocholanone is a pyrogen, causing fever mediated by interleukin-1 release. Elevated levels in urine have been associated with male pattern baldness. Source: Regenstrief LOINC

Fully-Specified Name

Component
Etiocholanolone/Androsterone
Property
SRto
Time
Pt
System
Urine
Scale
Qn
Method

Additional Names

Short Name
Etiocholanolone/Androsterone Ur-sRto
Display Name
Etiocholanolone/Androsterone (U) [Molar ratio]
Consumer Name Alpha
Etiocholanolone/Androsterone, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.58
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
73886-4 Steroid fractions panel - Urine

Member of these Groups

LG37444-3 Etiocholanolone/Androsterone|SRto|Urine

Language Variants Get Info

zh-CNChinese (China)
本胆烷醇酮/雄酮:物质的量比率:时间点:尿液:定量型:
nl-NLDutch (Netherlands)
etiocholanolon/androsteron:molaire verhouding:moment:urine:kwantitatief:
fr-FRFrench (France)
Étiocholanolone/androstérone:Moles ratio:Ponctuel:Urine:Numérique:
it-ITItalian (Italy)
Etiocolanolone/Androsterone:Srto:Pt:Urine:Qn:
es-MXSpanish (Mexico)
Etiocolanolona / Androsterona:Proporción de sustancia:Punto temporal:Orina:Cuantitativo:
es-ESSpanish (Spain)
Etiocolanolona/Androsterona:Relacion de Sustancia:Punto temporal:Orina:Qn:

Example Units

Unit Source
{ratio} Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=82881-4