LOINC
Version 2.73

82936-6Signal Recognition Particle (SRP) IgG Ab [Presence] in Serum by Line blotActive

Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC

Part Description

LP31710-4   Signal recognition particle
A cytosolic ribonucleoprotein complex that acts to induce elongation arrest of nascent presecretory and membrane proteins until the ribosome becomes associated with the rough endoplasmic reticulum. It consists of a 7S RNA and at least six polypeptide subunits (relative molecular masses 9, 14, 19, 54, 68, and 72K). Source: National Library of Medicine, MeSH 2006

Fully-Specified Name

Component
Signal recognition particle Ab.IgG
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Line blot

Additional Names

Short Name
SRP IgG Ser Ql Line blot
Display Name
Signal Recognition Particle (SRP) IgG Line blot Ql (S)
Consumer Name Alpha
Signal Recognition Particle (SRP) IgG antibody, Blood

Example Answer List LL2010-8

Source: Estonian Society of Laboratory Medicine

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
Borderline LA4259-3

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.66
Change Reason
This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
97561-5 Necrotizing myopathy autoimmune Ab panel - Serum

Member of these Groups

LG51136-6 Signal recognition particle Ab.IgG|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
信号识别颗粒 抗体.IgG:存在情况或阈值:时间点:血清:序数型:线点印迹法
nl-NLDutch (Netherlands)
signaalherkenningsdeeltje As.IgG:aanwezigheid:moment:serum:ordinaal:lijnblot
fr-CAFrench (Canada)
Particule reconnaissance signal , IgG:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoessai sur bandelette
fr-FRFrench (France)
SRP anticorps IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Blot en ligne
it-ITItalian (Italy)
Particella di riconoscimento del segnale Ab.IgG:PrThr:Pt:Siero:Ord:Line blot
es-MXSpanish (Mexico)
Partícula de reconocimiento de señal Ab.IgG:Presencia o umbral:Punto temporal:Suero:Ordinal:Mancha de línea
es-ESSpanish (Spain)
Particula de reconocimiento de señal (SRP) IgG:PrThr:Punto temporal:Suero:Ord:Line blot

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=82936-6