Glial nuclear type 1 IgG Ab [Presence] in Serum or Plasma by Line blot
This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC
LP71299-9 Glial nuclear type 1
Anti-glial nuclear antibody type 1 (AGNA-1) targets the Sox1 nuclear antigen found in Bergmann cells, a specialized glial cell type found in the cerebellar cortex. AGNA-1 antibodies are associated with paraneoplastic Lambert-Eaton myasthenic syndrome (LEMS) and paraneoplastic neuropathies associated with small cell lung cancer (SCLC). They have also been associated with non-paraneoplastic neuropathy, which may be an immune-mediated condition. PMID: 20701982 Source: Regenstrief LOINC, PMID: 20701982
- Glial nuclear type 1 Ab.IgG
- Line blot
- Short Name
- Glial nuc type 1 IgG SerPl Ql Line blot
- Display Name
- Glial nuclear type 1 IgG Line blot Ql
- Consumer Name Alpha Get Info
- Glial nuclear type 1 IgG antibody, Blood
Example Answer List: LL360-9Source: Regenstrief Institute
|PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)
|NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)
- First Released
- Version 2.58
- Last Updated
- Version 2.66
- Change Reason
- This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
- Order vs. Observation
Member of these Groups Get Info
|Glial nuclear type 1 Ab.IgG|
Language Variants Get Info
|Gliales de tipo nuclear 1 IgG:
|Glial nuclear tipo 1 Ab.IgG:
|Gliale nucléaire de type 1 , IgG:
|Noyau cellule gliale type 1 anticorps IgG:
|Gliali di tipo nucleare 1 Ab.IgG:
Synonyms: anticorpi IgG anticorpo Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
|gliaal nucleair type 1 As.IgG:
|神经胶质细胞核 1 型 抗体.IgG:
Synonyms: Ⅰ Ab.IgG;
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Copyright © 2023 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright