LOINC
Version 2.67

84926-5PCA-Tr Ab [Presence] in Serum by ImmunofluorescenceActive

Term Description

Antineuronal antibodies against PCA-Tr are detected and characterized based on immunofluorescence staining pattern on multiple neuronal, non-neuronal tissues, and transformed substrate cells.
Source: Regenstrief LOINC

Part Description

LP31709-6   Purkinje cell cytoplasmic type Tr
Purkinje cell cytoplasmic-Tr (PCA-Tr) antibodies are associated with Hodgkin's lymphoma. The clinical presentation that corresponds with PCA-Tr antibodies includes paraneoplastic cerebellar degeneration (PCD) and limbic encephalopathy (LE). [PMID: 22412264] PCD and LE are types of paraneoplastic neurological syndrome (PNS), an autoimmune disorder that is manifested by progressive neurological syndromes of any combination of the central, peripheral and autonomic nervous systems. The antibodies that attack the neural tissue develop in response to tumor cells. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies, testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed. [PMID: 22412264] Source: Regenstrief LOINC, Cytoplasmic

Fully-Specified Name

Component
Purkinje cell cytoplasmic type Tr Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IF

Additional Names

Short Name
PCA-Tr Ab Ser Ql IF
Display Name
PCA-Tr Ab IF Ql (S)

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.58
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Groups

LG29451-8 Purkinje cell cytoplasmic type Tr Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (CHINA)
浦肯雅细胞胞浆 Tr 型 抗体:存在情况或阈值:时间点:血清:序数型:免疫荧光法
nl-NLDutch (NETHERLANDS)
purkinjecellen type Tr As:aanwezigheid:moment:serum:ordinaal:immunofluorescentie
fr-BEFrench (BELGIUM)
Cellules de Purkinje type TR Ac:PrThr:Temps ponctuel:Sérum:Ordinal:Immunofluorescence
fr-CAFrench (CANADA)
Cellules de Purkinje cytoplasmique type Tr , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunofluorescence
fr-FRFrench (FRANCE)
Tr anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence
it-ITItalian (ITALY)
Cellule di Purkinje tipo Tr , Ab:PrThr:Pt:Siero:Ord:IF
ru-RURussian (RUSSIAN FEDERATION)
Пуркинье клетки тип Tr Ат:PrThr:ТчкВрм:Сыв:Пор:ИФ
es-ESSpanish (SPAIN)
Células de Purkinje tipo Tr Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunofluorescencia (IF)
tr-TRTurkish (TURKEY)
Purkinje hücreleri tip Tr Ab:MevcEşik:Zmlı:Ser:Srl:IF

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=84926-5