LOINC
Version 2.67

84928-1NMDAR subunit 1 Ab [Presence] in Serum by ImmunofluorescenceActive

Term Description

Antineuronal antibodies against NMDAR1 are detected and characterized based on immunofluorescence staining pattern on multiple neuronal, non-neuronal tissues, and transformed substrate cells.
Source: Regenstrief LOINC

Part Description

LP229977-6   N-methyl-D-aspartate receptor subunit 1
N-methyl-D-aspartate receptor 1 (NMDAR1) is subunit of NMDA receptors and belongs to the glutamate receptor channel superfamily. It is encoded by the GRIN1 (Glutamate [NMDA] receptor subunit zeta-1) gene located on chromosome 9q34.3.[UniProt: Q05586] Glutamate receptors are highly permeable to calcium and important for nervous system functioning. NMDAR1 antibodies are detected in patients with paraneoplastic syndromes, autoimmune encephalopathies and related conditions. Identification of specific antineuronal autoantibodies may direct evaluation for underlying malignancy. Characterization of autoantibody specificity may allow syndromic classification and assist in diagnosis and management. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, Aspartate (Wikipedia)

Fully-Specified Name

Component
N-methyl-D-aspartate receptor subunit 1 Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IF

Additional Names

Short Name
NMDAR1 Ab Ser Ql IF
Display Name
NMDAR subunit 1 Ab IF Ql (S)

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.58
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Groups

LG50948-5 N-methyl-D-aspartate receptor subunit 1 Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (CHINA)
N-甲基-D-天冬氨酸受体亚单位 1 抗体:存在情况或阈值:时间点:血清:序数型:免疫荧光法
nl-NLDutch (NETHERLANDS)
N-methyl-D-aspartaatreceptor subeenheid 1 As:aanwezigheid:moment:serum:ordinaal:immunofluorescentie
fr-FRFrench (FRANCE)
NMDAR1 IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence
it-ITItalian (ITALY)
N-metil-D-aspartato, subunità 1 recettore , Ab:PrThr:Pt:Siero:Ord:IF
es-ESSpanish (SPAIN)
Subunidad 1 del receptor de N-metil-D-aspartato (NMDAR-1) Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunofluorescencia (IF)

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=84928-1