LOINC
Version 2.72

85046-1AmpC beta-lactamase by cefoTEtan to cefoTEtan+cloxacillin inhibitory concentration ratio [Presence] by ARD gradient stripActive

Term Description

This term is used to report the presence or absence of AmpC beta-lactamase enzymes based on inhibitory concentrations of cefotetan and cefotetan+cloxacillin. This term was created for, but is not limited in use to, bioMerieux's ETEST AmpC assay.
Source: Regenstrief LOINC

Part Descriptions

LP232457-4   AmpC beta-lactamase by cefoTEtan to cefoTEtan+cloxacillin inhibitory concentration ratio
AmpC beta-lactamases (AmpCs) are resistance enzymes produced by pathogenic organisms such as E. coli. AmpC enzymes hydrolyze a variety of antimicrobials, including cephalosporins, penicillins, and aztreonam. The presence of AmpC can be detected by comparing the inhibitory concentration (IC) of cefotetan, which induces AmpC, with the IC of cefotetan+cloxacillin, in which cloxacillin is an AmpC inhibitor. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, Cefotetan (Wikipedia)

LP234471-3   Gradient strip ARD
A gradient strip is a reagent strip that contains a predefined concentration gradient of a specific antibiotic or combination of antibiotics that is used for antimicrobial susceptibility testing (AST) and antimicrobial resistance detection (ARD).
For AST, the result is reported in terms of the minimum inhibitory concentration (MIC) of a specific antimicrobial that prevents the visible growth of bacteria. In LOINC, the "Gradient strip" method is used for AST gradient strips that result in an MIC result.
For ARD, the result is reported as the presence or absence of a specific enzyme or other mechanism that confers resistance, which is determined based on comparing the inhibitory concentration (IC) of a specific antimicrobial with the IC of that antimicrobial plus a resistance inhibitor. In LOINC, the "Gradient strip ARD" method is used for ARD gradient strips, which are not intended for determining individual MIC values. Source: Regenstrief LOINC

Fully-Specified Name

Component
AmpC beta-lactamase by cefoTEtan to cefoTEtan+cloxacillin inhibitory concentration ratio
Property
PrThr
Time
Pt
System
Isolate
Scale
Ord
Method
Gradient strip ARD

Additional Names

Short Name
AmpC cefo + cefo-clox IC Islt Ql Grad
Display Name
AmpC beta-lactamase by cefoTEtan to cefoTEtan+cloxacillin inhibitory concentration ratio ARD gradient strip Ql (Isol)
Consumer Name Alpha
AmpC beta-lactamase by cefoTEtan to cefoTEtan+cloxacillin inhibitory concentration ratio

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.58
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (China)
头孢替坦相对于头孢替坦+克拉维酸抑菌浓度比值法 AmpC beta 内酰胺酶:存在情况或阈值:时间点:分离株:序数型:抗生素耐药性检测梯度胶条法
fr-FRFrench (France)
Ratio CMI bêta lactamase AmpC céfotétan/céfotétan+cloxacilline:Présence/Seuil:Ponctuel:Isolat:Qualitatif:Bandelette graduée ARD
it-ITItalian (Italy)
Rapporto tra la concentrazione inibitoria di AmpC-beta lattamasi del cefotetan/cefotetan+ cloxacillina:PrThr:Pt:Isolato:Ord:Striscia di gradiente ARD
es-MXSpanish (Mexico)
AmpC beta-lactamasa por cefoTEtan a cefoTEtan + cociente de concentración inhibidora de cloxacilina:Presencia o umbral:Punto temporal:Aislado:Ordinal:Tira degradada para la detección de resistencia a los antimicrobianos
es-ESSpanish (Spain)
AmpC beta-lactamasa para la concentración inhibitoria de cefotetan frente a la de cefotetan-cloxacilina:PrThr:Punto temporal:Aislado:Ord:Detercción de resistencia antimicrobiana por gradiente en tira.

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=85046-1