LOINC
Version 2.72

85047-9MBL by meropenem to meropenem-EDTA IC ratio [Presence] by ARD gradient stripActive

Term Description

This term is used to report the presence or absence of metallo beta-lactamase (MBL) enzymes based on inhibitory concentrations of meropenem and meropenem+EDTA. This term was created for, but is not limited in use to, bioMerieux's ETEST MBL assay.
Source: Regenstrief LOINC

Part Descriptions

LP232456-6   Metallo beta-lactamase by meropenem to meropenem+EDTA inhibitory concentration ratio
Metallo beta-lactamase (MBL) enzymes are resistance enzymes whose activity is dependent on divalent cations such as zinc or cadmium, so that they can be inhibited by metal chelators such as EDTA. The presence of MBLs can be detected by comparing the inhibitory concentration (IC) of a specific antimicrobial, such as imipenem or meropenem, with the IC of that antimicrobial plus EDTA. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, Meropenem (Wikipedia)

LP234471-3   Gradient strip ARD
A gradient strip is a reagent strip that contains a predefined concentration gradient of a specific antibiotic or combination of antibiotics that is used for antimicrobial susceptibility testing (AST) and antimicrobial resistance detection (ARD).
For AST, the result is reported in terms of the minimum inhibitory concentration (MIC) of a specific antimicrobial that prevents the visible growth of bacteria. In LOINC, the "Gradient strip" method is used for AST gradient strips that result in an MIC result.
For ARD, the result is reported as the presence or absence of a specific enzyme or other mechanism that confers resistance, which is determined based on comparing the inhibitory concentration (IC) of a specific antimicrobial with the IC of that antimicrobial plus a resistance inhibitor. In LOINC, the "Gradient strip ARD" method is used for ARD gradient strips, which are not intended for determining individual MIC values. Source: Regenstrief LOINC

Fully-Specified Name

Component
Metallo beta-lactamase by meropenem to meropenem+EDTA inhibitory concentration ratio
Property
PrThr
Time
Pt
System
Isolate
Scale
Ord
Method
Gradient strip ARD

Additional Names

Short Name
MBL mero + mer-EDTA IC rto Islt Ql Grad
Display Name
MBL by meropenem to meropenem-EDTA IC ratio ARD gradient strip Ql (Isol)
Consumer Name Alpha
MBL by Meropenem to Meropenem-EDTA IC Ratio

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.58
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (China)
美罗培南相对于美罗培南+EDTA抑菌浓度比值法金属 beta 内酰胺酶:存在情况或阈值:时间点:分离株:序数型:抗生素耐药性检测梯度胶条法
fr-FRFrench (France)
Ratio CMI métallo bêta lactamase méropénème/EDTA:Présence/Seuil:Ponctuel:Isolat:Qualitatif:Bandelette graduée ARD
it-ITItalian (Italy)
Rapporto concentrazione inibitoria metallo beta-lattamasi mediante meropenem/imeropenem+EDTA:PrThr:Pt:Isolato:Ord:Striscia di gradiente ARD
es-MXSpanish (Mexico)
Relación de concentración inhibidora de metalo betalactamasa por meropenem a meropenem + EDTA:Presencia o umbral:Punto temporal:Aislado:Ordinal:Tira degradada para la detección de resistencia a los antimicrobianos
es-ESSpanish (Spain)
ESBL para la concentración inhibitoria de meropenem frente a la de meropenem-EDTA:PrThr:Punto temporal:Aislado:Ord:Detercción de resistencia antimicrobiana por gradiente en tira.

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=85047-9