85047-9MBL by meropenem to meropenem-EDTA IC ratio [Presence] by ARD gradient stripActive
Term Description
This term is used to report the presence or absence of metallo beta-lactamase (MBL) enzymes based on inhibitory concentrations of meropenem and meropenem+EDTA. This term was created for, but is not limited in use to, bioMerieux's ETEST MBL assay.
Source: Regenstrief LOINC
Part Descriptions
LP232456-6 Metallo beta-lactamase by meropenem to meropenem+EDTA inhibitory concentration ratio
Metallo beta-lactamase (MBL) enzymes are resistance enzymes whose activity is dependent on divalent cations such as zinc or cadmium, so that they can be inhibited by metal chelators such as EDTA. The presence of MBLs can be detected by comparing the inhibitory concentration (IC) of a specific antimicrobial, such as imipenem or meropenem, with the IC of that antimicrobial plus EDTA.
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Source: Regenstrief LOINC, Meropenem (Wikipedia)
LP234471-3 Gradient strip ARD
A gradient strip is a reagent strip that contains a predefined concentration gradient of a specific antibiotic or combination of antibiotics that is used for antimicrobial susceptibility testing (AST) and antimicrobial resistance detection (ARD).
For AST, the result is reported in terms of the minimum inhibitory concentration (MIC) of a specific antimicrobial that prevents the visible growth of bacteria. In LOINC, the "Gradient strip" method is used for AST gradient strips that result in an MIC result.
For ARD, the result is reported as the presence or absence of a specific enzyme or other mechanism that confers resistance, which is determined based on comparing the inhibitory concentration (IC) of a specific antimicrobial with the IC of that antimicrobial plus a resistance inhibitor. In LOINC, the "Gradient strip ARD" method is used for ARD gradient strips, which are not intended for determining individual MIC values.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Metallo beta-lactamase by meropenem to meropenem+EDTA inhibitory concentration ratio
- Property
- PrThr
- Time
- Pt
- System
- Isolate
- Scale
- Ord
- Method
- Gradient strip ARD
Additional Names
- Short Name
- MBL mero + mer-EDTA IC rto Islt Ql Grad
- Display Name
- MBL by meropenem to meropenem-EDTA IC ratio ARD gradient strip Ql (Isol)
- Consumer Name Alpha
- MBL by Meropenem to Meropenem-EDTA IC Ratio
Example Answer List LL744-4
Source: Regenstrief Institute
Answer | Code | Score | Answer ID |
---|---|---|---|
Detected | LA11882-0 | ||
Not detected | LA11883-8 |
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 2.58
- Last Updated
- Version 2.58
- Order vs. Observation
- Both
Language Variants Get Info
- zh-CNChinese (China)
- 美罗培南相对于美罗培南+EDTA抑菌浓度比值法金属 beta 内酰胺酶:
存在情况或阈值: 时间点: 分离株: 序数型: 抗生素耐药性检测梯度胶条法 - fr-FRFrench (France)
- Ratio CMI métallo bêta lactamase méropénème/EDTA:
Présence/Seuil: Ponctuel: Isolat: Qualitatif: Bandelette graduée ARD - it-ITItalian (Italy)
- Rapporto concentrazione inibitoria metallo beta-lattamasi mediante meropenem/imeropenem+EDTA:
PrThr: Pt: Isolato: Ord: Striscia di gradiente ARD - es-MXSpanish (Mexico)
- Relación de concentración inhibidora de metalo betalactamasa por meropenem a meropenem + EDTA:
Presencia o umbral: Punto temporal: Aislado: Ordinal: Tira degradada para la detección de resistencia a los antimicrobianos - es-ESSpanish (Spain)
- ESBL para la concentración inhibitoria de meropenem frente a la de meropenem-EDTA:
PrThr: Punto temporal: Aislado: Ord: Detercción de resistencia antimicrobiana por gradiente en tira.
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=85047-9
LOINC Copyright
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