LOINC
Version 2.67

85092-5Autoimmune liver diseases IgG panel - Serum or Plasma by Line blotActive

Term Description

This panel contains results for the presence of IgG autoantibodies in serum or plasma for the diagnosis of autoimmune liver diseases, including autoimmune hepatitis and primary biliary cirrhosis. This panel was created for, but not limited in use to, the submitter's test strip, a membrane strip pre-coated with the following antigens: AMA-M2, M2-3E, Sp100, PML, gp210, LKM-1, LC-1, SLA/LP, SS-A, Ro-52, Scl-70, CENP A, CENP B and PGDH. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC

Panel Hierarchy
Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
85092-5 Autoimmune liver diseases IgG panel - Serum or Plasma by Line blot
Indent72318-9 Centromere protein A IgG Ab [Presence] in Serum or Plasma by Immunoassay
Indent82913-5 Centromere protein B IgG Ab [Presence] in Serum by Line blot
Indent85095-8 D-3-phosphoglycerate dehydrogenase IgG Ab [Presence] in Serum by Line blot
Indent82921-8 Liver cytosol IgG Ab [Presence] in Serum by Line blot
Indent69952-0 Liver kidney microsomal 1 IgG Ab [Presence] in Serum by Immunoassay
Indent82928-3 Mitochondria M2 IgG Ab [Presence] in Serum by Line blot
Indent72320-5 Mitochondria M2-3E IgG Ab [Presence] in Serum by Immunoassay
Indent82931-7 Nuclear pore protein gp210 IgG Ab [Presence] in Serum by Line blot
Indent82923-4 PML IgG Ab [Presence] in Serum by Line blot
Indent17570-3 SCL-70 extractable nuclear IgG Ab [Presence] in Serum by Immunoassay
Indent82933-3 Sjogrens syndrome-A extractable nuclear 52kD IgG Ab [Presence] in Serum by Line blot
Indent17585-1 Sjogrens syndrome-A extractable nuclear IgG Ab [Presence] in Serum by Immunoassay
Indent78433-0 Soluble liver IgG Ab [Presence] in Serum by Line blot
Indent82932-5 sp100 IgG Ab [Presence] in Serum by Line blot

Fully-Specified Name

Component
Autoimmune liver diseases Ab.IgG panel
Property
-
Time
Pt
System
Ser/Plas
Scale
-
Method
Line blot

Additional Names

Short Name
Liver diseases IgG Pnl SerPl Line blot
Display Name
Autoimmune liver diseases IgG panel Line blot

Basic Attributes

Class
PANEL.SERO
Type
Laboratory
First Released
Version 2.58
Last Updated
Version 2.67
Change Reason
This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
Order vs. Observation
Order
Panel Type
Panel

Language Variants Get Info

zh-CNChinese (CHINA)
自身免疫性肝病抗体.IgG 组套:-:时间点:血清/血浆:-:线点印迹法
nl-NLDutch (NETHERLANDS)
autoimmuun leverziekten As.IgG panel:-:moment:serum of plasma:-:lijnblot
fr-CAFrench (CANADA)
Hépatite auto-immune d'anticorps.IgG:-:Temps ponctuel:Sérum/Plasma:-:Immunoessai sur bandelette
fr-FRFrench (FRANCE)
Maladies autoimmunes du foie anticorps IgG panel:-:Ponctuel:Sérum/Plasma:-:Blot en ligne
es-ESSpanish (SPAIN)
Panel de anticuerpos IgG de enfermedades hepáticas autoinmunes:Propiedades mixtas (sólo paneles):Punto temporal:Suero o Plasma:-:Line blot

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=85092-5