Version 2.73

85360-6Bordetella pertussis+bronchiseptica+holmesii IS481 DNA [Presence] in Nasopharynx by NAA with non-probe detectionActive

Term Description

This test is primarily for the detection of the IS481 insertional element DNA of the Bordetella pertussis genome in human nasopharyngeal swab samples taken from patients suspected of having respiratory tract infection caused by B. pertussis. The IS481 insertion sequence can also be found in B. holmesii and B. bronchiseptica strains, so respiratory infections with either Bordetella pertussis, B. holmesii or B. bronchiseptica may yield positive test results in this assay, which does not differentiate between these strains. Since B. pertussis and B. holmesii present with similar clinical symptoms, additional testing would need to be performed to differentiate between these strains. This term was created for, but not limited in use to, the illumigene Pertussis DNA Amplification Assay, which uses loop-mediated isothermal DNA amplification (LAMP) technology to detect the IS481 insertional element.
Source: Regenstrief LOINC

Part Description

LP247783-6   Bordetella pertussis+bronchiseptica+holmesii IS481
A repetitive insertion sequence, IS481, has been found to be present in up to 100 copies within the genome of B. pertussis. In B. holmesii, 8-10 copies of this insertion sequence can be found.[PMID:11326023] On rare occasion, the B. bronchiseptica genome may contain a copy of this sequence. Thus, all these species may test positive in assays targeting the IS481 sequence. Concurrent culturing is used to differentiate species from B. pertussis and confirm the organism, while targeted DNA testing allows preliminary results to be reported the same day that the specimen is received. Source: Regenstrief LOINC

Fully-Specified Name

Bordetella pertussis+bronchiseptica+holmesii IS481 DNA

Additional Names

Short Name
B pert+bron+holm IS481 Nph NAA+non-Probe
Display Name
B. pertussis+bronchiseptica+holmesii IS481 DNA NAA+non-probe Ql (Nph)
Consumer Name Alpha
Bordetella pertussis+bronchiseptica+holmesii IS481, Nasopharynx

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.61
Last Updated
Version 2.63
Order vs. Observation

Member of these Panels

LOINC Long Common Name
82159-5 Respiratory pathogens DNA and RNA panel - Nasopharynx by NAA with non-probe detection

Member of these Groups

LG50886-7 Bordetella pertussis+bronchiseptica+holmesii IS481 DNA|PrThr|Sys:ANYResp

Language Variants Get Info

zh-CNChinese (China)
百日咳博德特菌+支气管败血性百日咳博德特菌+霍氏博德特菌 IS481 DNA:存在情况或阈值:时间点:鼻咽:序数型:非探针法.基因扩增.靶向
fr-FRFrench (France)
Bordetella pertussis+bronchiseptica+holmesii IS481 ADN:Présence/Seuil:Ponctuel:Nasopharynx:Qualitatif:Non-PCR amplification de cible
it-ITItalian (Italy)
Bordetella pertussis+bronchiseptica+holmesii IS481 DNA:PrThr:Pt:Nph:Ord:Non-sonda.amp.tar
es-MXSpanish (Mexico)
Bordetella pertussis + bronchiseptica + holmesii IS481 ADN:Presencia o umbral:Punto temporal:Nasofaringe:Ordinal:Amplificación de ácidos nucleicos con detección sin sonda
es-ESSpanish (Spain)
Bordetella pertussis+bronchiseptica+holmesii IS481 ADN:PrThr:Punto temporal:Nasofaringe:Ord:Amplificación del objetivo no basado en sonda

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