LOINC
Version 2.67

85365-5Neutrophil membrane Ab [Presence] in Serum by ImmunofluorescenceActive

Term Description

The results of this test are determined by immunofluorescent patterns.
Source: Regenstrief LOINC

Part Description

LP231983-0   Neutrophil membrane Ab
Antineutrophil membrane antibodies are antibodies that bind to antigens on the surface of neutrophils. Several specific antigens have been identified, but the IgG Fc receptor type 3b is the primary target. It was first recognized that these antibodies were a cause of autoimmune neutropenia (AIN) in 1975. Neutropenia is separated into three categories according to the risk of infection and based on the concentration of circulating neutrophils: mild neutropenia (1000-1500 cells/uL) moderate neutropenia (500-1000 cells/uL) and severe (less than 500 cells/uL). In some AIN the neutrophil numbers are normal but some functions are compromised including their ability to influence adhesion, aggregation, chemotaxis, phagocytosis and metabolic activation. AIN has two subcategories including primary AIN and secondary AIN. In primary AIN there is no association with another pathology. Primary AIN is most common in neonates and results in moderate to severe neutropenia, rarely leads to infection and is self-limiting. Secondary AIN usually occurs following a systemic haematologic disease including infectious diseases, solid or haematological neoplasms, neurological diseases, bone marrow or stem cell transplants, kidney transplants and the use of some drugs. In light of the difficulty in detecting autoimmune antineutrophil antibodies, it is recommended that both immunofluorescent and agglutination tests be performed. [PMID: 16207350] Source: Regenstrief LOINC

Fully-Specified Name

Component
Neutrophil membrane Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IF

Additional Names

Short Name
Neutrophil membrane Ab Ser Ql IF
Display Name
Neutrophil membrane Ab IF Ql (S)

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.61
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Language Variants Get Info

zh-CNChinese (CHINA)
嗜中性粒细胞膜 抗体:存在情况或阈值:时间点:血清:序数型:免疫荧光法
nl-NLDutch (NETHERLANDS)
neutrofiel membraan As:aanwezigheid:moment:serum:ordinaal:immunofluorescentie
fr-FRFrench (FRANCE)
Membrane des polynucléaires neutrophiles anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence
it-ITItalian (ITALY)
Membrana neutrofili , Ab:PrThr:Pt:Siero:Ord:IF
es-ESSpanish (SPAIN)
Membrana neutrófila Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunofluorescencia (IF)

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=85365-5