Beta-lactam resistance ESBL blaCTX-M-9 Group gene [Presence] by Molecular method
This test reports the presence of the CTX-M9 extended spectrum beta lactamase gene in gram negative bacterial isolates. This term was created for, but is not limited in use to, the submitter's modified protocol for the Check-Points Check-MDR CT103XL assay.
Source: Regenstrief LOINC
LP248280-2 Bacterial beta-lactam resistance ESBL blaCTX-M-9 Group gene
Extended-spectrum beta-lactamases (ESBL) are enzymes produced by some bacteria that are resistant to the majority of beta-lactam antibiotics which include the penicillins, cephalosporins and the monobactam aztreonam. [https://www.uptodate.com/contents/extended-spectrum-beta-lactamases] Organisms producing CTX-M type ESBL enzymes have been isolated worldwide with more than 150 enzymes identified. These enzymes have been classified into seven major phylogenetic groups: CTX-M -1, CTX-M-2, CTX-M-8, CTX-M-9, CTX-M-25, CTX-M-74 and CTX-M-75. The rare ESBL type CTX-M-8 has been isolated in Germany, mainly in E. coli, but also in Salmonella and E. aerogenes. CTX-M type ESBL have been isolated worldwide and their incidence has increased dramatically and is still increasing leading to a major therapeutic issue. Currently more than 150 allelic variants of CTX-M have been identified. These enzymes are classified in five major phylogenetic groups based on their gene sequences: CTX-M -1, CTX-M-2, CTX-M-8, CTX-M-9, CTX-M-25; two additional groups have been reported recently: CTX-M-74 and CTX-M-75. The dissemination of these enzymes has caused an increased use of carbapenems for treatment of infections which carries its own risk of furthering resistance. PMID: 25234380 The genes are named with the prefix "bla", which stands for "beta-lactam", followed by the enzyme, for example, blaCTX-M-1. Source: Regenstrief LOINC
- Bacterial beta-lactam resistance ESBL blaCTX-M-9 group gene
- Short Name
- ESBL blaCTX-M9 Grp gene Islt/Spm Ql
- Display Name
- Beta-lactam resistance ESBL blaCTX-M-9 Group gene Molgen Ql (Islt/Spec)
- Consumer Name Alpha Get Info
- Beta-lactam Resistance ESBL blaCTX-M-9 Group gene
Example Answer List: LL360-9Source: Regenstrief Institute
|PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)
|NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)
- First Released
- Version 2.61
- Last Updated
- Version 2.67
- Change Reason
- Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
- Order vs. Observation
Member of these Panels
|Long Common Name
|Gram negative bacterial resistance panel by Molecular genetics method
Language Variants Get Info
|Bakterielle Beta-Lactam-Resistenz ESBL blaCTX-M-9-Gruppe-Gen:
Synonyms: Extended Spectrum beta-lactamases
|Grupo genes bacterianos ESBL blaCTX-M-9 resistente a beta-lactámicos:
|Gen del grupo BLEE blaCTX-M-9 de resistencia bacteriana a betalactámicos:
|Résistance bactérienne aux bêta lactamases ESBL blaCTX-M-9 groupe gène:
|Resistenza batterica beta-lactamica, gene Gruppo ESBL blaCTX-M-9:
Synonyms: Gene Gruppo ESBL blaCTX-M-9 di resistenza batteric Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici
|bacteriële bètalactamresistentie ESBL blaCTX-M-9 groep gen:
Synonyms: isolaat/specimen molgen
|细菌 beta-内酰胺耐药 ESBL blaCTX-M-9 组基因:
Synonyms: B M 型 β 供检查用的材料;
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