Version 2.77

Term Description

This test reports the presence of the CTX-M9 extended spectrum beta lactamase gene in gram negative bacterial isolates. This term was created for, but is not limited in use to, the submitter's modified protocol for the Check-Points Check-MDR CT103XL assay.
Source: Regenstrief LOINC

Part Description

LP248280-2   Bacterial beta-lactam resistance ESBL blaCTX-M-9 Group gene
Extended-spectrum beta-lactamases (ESBL) are enzymes produced by some bacteria that are resistant to the majority of beta-lactam antibiotics which include the penicillins, cephalosporins and the monobactam aztreonam. [] Organisms producing CTX-M type ESBL enzymes have been isolated worldwide with more than 150 enzymes identified. These enzymes have been classified into seven major phylogenetic groups: CTX-M -1, CTX-M-2, CTX-M-8, CTX-M-9, CTX-M-25, CTX-M-74 and CTX-M-75. The rare ESBL type CTX-M-8 has been isolated in Germany, mainly in E. coli, but also in Salmonella and E. aerogenes. CTX-M type ESBL have been isolated worldwide and their incidence has increased dramatically and is still increasing leading to a major therapeutic issue. Currently more than 150 allelic variants of CTX-M have been identified. These enzymes are classified in five major phylogenetic groups based on their gene sequences: CTX-M -1, CTX-M-2, CTX-M-8, CTX-M-9, CTX-M-25; two additional groups have been reported recently: CTX-M-74 and CTX-M-75. The dissemination of these enzymes has caused an increased use of carbapenems for treatment of infections which carries its own risk of furthering resistance. PMID: 25234380 The genes are named with the prefix "bla", which stands for "beta-lactam", followed by the enzyme, for example, blaCTX-M-1. Source: Regenstrief LOINC

Fully-Specified Name

Bacterial beta-lactam resistance ESBL blaCTX-M-9 group gene

Additional Names

Short Name
ESBL blaCTX-M9 Grp gene Islt/Spm Ql
Display Name
Beta-lactam resistance ESBL blaCTX-M-9 Group gene Molgen Ql (Islt/Spec)
Consumer Name Alpha Get Info
Beta-lactam Resistance ESBL blaCTX-M-9 Group gene

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.61
Last Updated
Version 2.67
Change Reason
Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
Order vs. Observation

Member of these Panels

LOINC Long Common Name
93698-9 Gram negative bacterial resistance panel by Molecular genetics method

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Bakterielle Beta-Lactam-Resistenz ESBL blaCTX-M-9-Gruppe-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Isolat oder Probenmaterial:Ordinal:Molekulargenetisch
Synonyms: Extended Spectrum beta-lactamases
es-ES Spanish (Spain) Grupo genes bacterianos ESBL blaCTX-M-9 resistente a beta-lactámicos:PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular
es-MX Spanish (Mexico) Gen del grupo BLEE blaCTX-M-9 de resistencia bacteriana a betalactámicos:Presencia o umbral:Punto temporal:Aislado o espécimen:Ordinal:Genética molecular
fr-FR French (France) Résistance bactérienne aux bêta lactamases ESBL blaCTX-M-9 groupe gène:Présence/Seuil:Ponctuel:Isolat/échantillon:Qualitatif:Biologie moléculaire
it-IT Italian (Italy) Resistenza batterica beta-lactamica, gene Gruppo ESBL blaCTX-M-9:PrThr:Pt:Isolato/Campione:Ord:Molgen
Synonyms: Gene Gruppo ESBL blaCTX-M-9 di resistenza batteric Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici
nl-NL Dutch (Netherlands) bacteriële bètalactamresistentie ESBL blaCTX-M-9 groep gen:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek
Synonyms: isolaat/specimen molgen
zh-CN Chinese (China) 细菌 beta-内酰胺耐药 ESBL blaCTX-M-9 组基因:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法
Synonyms: B M 型 β 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内,用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 分离株/标本(样本、样品、试样) 分离物;分离菌;分离菌株;隔离种群 受检物 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 抗力 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 抗耐性 抵抗力 抵抗性 时刻;随机;随意;瞬间 样品 样本 电阻 细菌 beta-内酰胺(β-内酰胺)耐药(抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型) ESBL(超广谱β-内酰胺酶) blaCTX-M-9 组基因 细菌性 细菌的 耐性 试样 贝塔 遗传基因;遗传因子;吉恩;生物基因 阻力

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup$lookup?system=