LOINC
Version 2.67

85839-9Beta-lactam resistance ESBL blaTEM gene [Presence] by Molecular methodActive

Term Description

This test reports the presence of the TEM extended spectrum beta lactamase gene in gram negative bacterial isolates. This term was created for, but is not limited in use to, the submitter's modified protocol for the Check-Points Check-MDR CT103XL assay.
Source: Regenstrief LOINC

Part Description

LP248285-1   Bacterial beta-lactam resistance ESBL blaTEM gene
Extended-spectrum beta-lactamases (ESBL) are enzymes produced by some gram negative bacilli that confer resistance to the majority of beta-lactam antibiotics, include the penicillins, cephalosporins and the monobactam aztreonam. ESBLs are most often plasmid-borne. Specific ESBLs include TEM, SHV, and the CTX-M groups, which are the most clinically prevalent, and VEB, PER, BEL, and GES, which are less common. [PMID: 19246801] -TEM and SHV subtypes are derived from amino acid substitutions, resulting in enzymatic hydrolysis of many beta-lactam antibiotics. -CTX-M genes originate from Kluyvera species. They are separated based on their amino acid sequences into the following groups: CTX-M-1, CTX-M-2, CTX-M-9, CTX-M-8, and CTX-M-25. -VEB, PER, BEL, and GES genes are less common. [Mayo Medical Laboratories] The nomenclature for ESBL genes includes the prefix "bla", which stands for "beta-lactam", followed by the enzyme (ie. blaTEM). Source: Regenstrief LOINC

Fully-Specified Name

Component
Bacterial beta-lactam resistance ESBL blaTEM gene
Property
PrThr
Time
Pt
System
Isolate/Specimen
Scale
Ord
Method
Molgen

Additional Names

Short Name
ESBL blaTEM gene Islt/Spm Ql
Display Name
Beta-lactam resistance ESBL blaTEM gene Molgen Ql (Islt/Spec)

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.67
Change Reason
Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
Order vs. Observation
Observation

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
93698-9 Gram negative bacterial resistance panel by Molecular genetics method

Language Variants Get Info

zh-CNChinese (CHINA)
细菌 beta-内酰胺耐药 ESBL blaTEM 基因:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法
nl-NLDutch (NETHERLANDS)
bacterieel bèta-lactamresistentie ESBL blaTEM-gen:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek
fr-FRFrench (FRANCE)
Résistance bactérienne aux bêta lactamases ESBL blaTEM gène:Présence/Seuil:Ponctuel:Isolat:Qualitatif:PCR amplification de cible
it-ITItalian (ITALY)
Resistenza batterica beta-lactamica, gene ESBL blaTEM:PrThr:Pt:Isolato/Campione:Ord:Molgen
es-ESSpanish (SPAIN)
gen bacteriano ESBL blaTEM resistente a beta-lactámicos:PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=85839-9