86202-9Porcine epidemic diarrhea virus [Presence] in Tissue by Immune stainActive
Sample types for this test include formalin-fixed, paraffin-embedded tissue samples, frozen samples, or cell smears/cultures.
Source: Regenstrief LOINC
LP182479-8 Porcine epidemic diarrhea virus
Porcine Epidemic Diarrhea Virus (PEDv) is a large-enveloped RNA virus, which is a member of the genus Alphacoronavirus within the Coronaviridae family. The complete PEDv genome consists of 5 gene segments: open reading frame 1 (ORF1), spike (S), envelope (E), membrane (M), and nucleocapsid (N). It is encapsulated by a single N protein. The S protein contributes to the stimulation of neutralizing antibodies in the infected host. Its association to adapted growth in vitro and attenuation in vivo lends itself to use for genetic comparison among PEDV isolates and effective vaccines. The M protein is required for assembly and can also induce the production of virus-neutralizing antibodies. The E protein contributes to coronavirus budding. The N protein has functions associated with viral replication and pathogenesis.
PEDv causes viral enteritis, which leads to the destruction of villus enterocytes in pigs of all ages. It is spread by the ingestion of feces from infected pigs, resulting in vomiting, watery diarrhea, dehydration, and high mortality, especially in nursery piglets. Disease caused by PEDv is clinically similar to that caused by Transmissible gastroenteritis coronavirus (TGEV) [PMID: 26689811]
At least two PEDv strains have been identified in the USA: the US PEDv prototype and S INDEL variant. The INDEL variant PEDv strain has insertions and deletions (INDELs) in the spike (S) gene. [PMID: 25279722] The INDEL strain is related to milder clinical signs than prototype strains. [PMID: 24750580] [PMID: 26748596] The genomic differences in the S gene between the US PEDv prototype and INDEL variant may be responsible for the virulence differences. Potential targets when testing for PEDv RNA include the nucleocapsid protein (N) gene and the ~2500 bp fragment of the S-gene. Source: Regenstrief LOINC
- Porcine epidemic diarrhea virus
- Immune stain
- Short Name
- PEDv Tiss Ql ImStn
- Display Name
- Porcine epidemic diarrhea virus Immune stain Ql (Tiss)
- First Released
- Version 2.61
- Last Updated
- Version 2.63
- Change Reason
- Updated System from "Tissue" to "Tiss" to be consistent with other laboratory tissue terms.
- Order vs. Observation
Example Answer List LL360-9
Source: Regenstrief Institute
|Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value)||LA6576-8|
|Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value)||LA6577-6|
Language Variants Get Info
- zh-CNChinese (CHINA)
存在情况或阈值: 时间点: 组织与涂片: 序数型: 免疫染色法
- nl-NLDutch (NETHERLANDS)
- Varkens epidemic diarrhea virus:
aanwezigheid: moment: weefsel en uitstrijkjes: ordinaal: immunokleuring
- it-ITItalian (ITALY)
- Virus della diarrea epidemica suina:
PrThr: Pt: Tessuto: Ord: Colorazione immunologica
- ru-RURussian (RUSSIAN FEDERATION)
- Свиная эпидемическая диаррея вирус:
PrThr: ТчкВрм: Тк: Пор: Иммуногистохимическая окраска
- es-ESSpanish (SPAIN)
- Virus de la diarrea epidémica porcina:
PrThr: Punto temporal: Tejido: Ord: Tinción de inmunohistoquímica
- tr-TRTurkish (TURKEY)
- Porsin epidemik diyare virüsü:
MevcEşik: Zmlı: Doku: Srl: İmmün boyama
LOINC FHIR® API Example - CodeSystem Request Get Info
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Copyright © 2019 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright