LOINC
Version 2.72

86318-3Influenza virus B Yamagata lineage Ag [Presence] in Isolate by Hemagglutination inhibitionActive

Part Descriptions

LP182338-6   Influenza virus B Yamagata lineage
Influenza B viruses can be separated into two major lineages, B/Victoria and B/Yamagata. Recent studies have shown that the two major lineages may differ in terms of epidemiology and risk of secondary infection. One study found that patients with confirmed influenza B Victoria lineage infections were significantly younger compared to patients infected with the Yamagata lineage.[PMID:25034374] A separate study found that Victoria-lineage viruses were associated with a significantly higher risk of secondary infection among patients' household contacts who were 15 years old or younger than among those older than 15, but the same did not hold true for Yamagata-lineage viruses.[PMID:26400854] Studies have also shown that genetically distinct lineages like B/Victoria/2/87 can cocirculate in the population and that the reassortment among these strains plays a role in generating the genetic diversity of influenza B viruses. [PMID:16891481] Source: Regenstrief LOINC

LP6304-2   HAI
The hemagglutination-inhibition assay (HAI) can be used to identify subtypes of hemagglutinin producing viruses, such as Influenza. HAI can also be used to identify the subtype-specificity of antibodies against the virus. Normally, Influenza's hemagglutinin glycoprotein binds to receptors on the surface of red blood cells, causing them to agglutinate. If antibodies specific to the virus are present in the patient sample, they will bind to the virus, which prevents the virus from binding to the red blood cells and therefore prevents agglutination. To determine which subtype of virus is present, a viral isolate is tested against a series of antibodies with known subtype specificities. Whichever antibody inhibits red cell agglutination identifies the viral subtype. Similarly, antibody specificity is identified by testing the patient sample against known virus subtypes. [PMID:24899416] Source: Regenstrief LOINC, B blood group

Fully-Specified Name

Component
Influenza Virus B Yamagata lineage Ag
Property
PrThr
Time
Pt
System
Isolate
Scale
Ord
Method
HAI

Additional Names

Short Name
FLUBV Yam Ag Islt Ql HAI
Display Name
FLUBV Yam Ag HAI Ql (Isol)
Consumer Name Alpha
Influenza B Yam antigen

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.61
Order vs. Observation
Observation

Member of these Groups

LG32757-3 Influenza virus

Language Variants Get Info

zh-CNChinese (China)
流感病毒 B 型 Yamagata 谱系 抗原:存在情况或阈值:时间点:分离株:序数型:红细胞凝集抑制试验法
nl-NLDutch (Netherlands)
Influenzavirus B Yamagata lineage Ag:aanwezigheid:moment:isolaat:ordinaal:hemagglutinatieremming
fr-FRFrench (France)
Influenza virus B lignée Yamagata Ag:Présence/Seuil:Ponctuel:Isolat:Qualitatif:Hémagglutination indirecte
it-ITItalian (Italy)
Influenza B, virus , Ag:PrThr:Pt:Isolato:Ord:HAI
es-MXSpanish (Mexico)
Virus de la influenza B linaje Yamagata Ag:Presencia o umbral:Punto temporal:Aislado:Ordinal:Inhibición de la hemaglutinación
es-ESSpanish (Spain)
Linaje Virus Influenza B Yamagata Antígeno:PrThr:Punto temporal:Aislado:Ord:Inhibición de la Hemaglutinación
tr-TRTurkish (Turkey)
Influenza virus B Yamagata lineage Ag:MevcEşik:Zmlı:İzolat:Srl:HAI

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=86318-3