LOINC
Version 2.67

86453-8O-nortramadol [Presence] in UrineActive

Part Description

LP173437-7   O-nortramadol
O-desmethyltramadol (M1) is an active metabolite of tramadol which is a narcotic analgesic used to treat severe pain. [PubChem: Tramadol] Tramadol and M1 work synergistically to relieve pain. M1 activates the opioid receptor responsible for the analgesic effect of tramadol. The parent drug prevents reuptake of norepinephrine and serotonin which inhibits pain signal transmission in the spinal cord. M1 metabolism is highly dependent upon CYP2D6 which influences the efficacy of pain relief experienced by the patient. The predominant adverse side effects associated with tramadol use include nausea, vomiting, sweating, itching, constipation, headache and central nervous system stimulation.(http://boris.unibe.ch/69119/1/01213011-201407000-00007.pdf) Source: Regenstrief LOINC

Fully-Specified Name

Component
O-nortramadol
Property
PrThr
Time
Pt
System
Urine
Scale
Ord
Method

Additional Names

Short Name
O-nortramadol Ur Ql
Display Name
O-nortramadol Ql (U)

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.61
Order vs. Observation
Observation

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Groups

LG37717-2 O-nortramadol|ANYProp|ANYTm|ANYSys|ANYMeth

Language Variants Get Info

zh-CNChinese (CHINA)
O-去甲基曲马多:存在情况或阈值:时间点:尿液:序数型:
nl-NLDutch (NETHERLANDS)
O-desmethyltramadol:aanwezigheid:moment:urine:ordinaal:
fr-FRFrench (FRANCE)
O-nortramadol:Présence/Seuil:Ponctuel:Urine:Qualitatif:
it-ITItalian (ITALY)
O-nortramadolo:PrThr:Pt:Urine:Ord:
ru-RURussian (RUSSIAN FEDERATION)
O-дезметилтрамадол:PrThr:ТчкВрм:Моча:Пор:
es-ESSpanish (SPAIN)
O-Desmetiltramadol:PrThr:Punto temporal:Orina:Ord:
tr-TRTurkish (TURKEY)
O-dezmetiltramadol:MevcEşik:Zmlı:İdrar:Srl:

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=86453-8