LOINC
Version 2.67

86455-3Brucella sp Ab [Presence] in Serum by Acidified buffered plate agglutinationActive

Part Descriptions

LP14160-3   Brucella sp
Brucella are gram-negative coccobacilli that commonly infect cows (Brucella abortus), pigs (Brucella suis), goats (Brucella melitensis), and dogs (Brucella canis), along with wild animals such as deer, elk, and moose. The main pathogenic species of Brucella are Brucella melitensis, Brucella suis and Brucella abortus. Brucella melitensis is a gram-negative coccobacillus bacterium from the Brucellaceae family. It mainly affects the reproductive tract of goats and sheep, and in some regions is the major cause of abortion in them. It can also negatively impact fertility and lactation over time. B. melitensis has the broadest host range, infecting cattle, camels and dogs, in addition to sheep, goats and humans. Brucella suis infections in pigs causes chronic inflammatory lesions in the reproductive organs or orchitis and may affect joints and/or other organs. Similar to B. melitensis, B. suis can cause abortion in pregnant hosts. Other impacts of the disease are sterility, posterior paralysis and spondylitis. It is transmitted mainly by ingestion of infected tissues or fluids. It can cause undulant fever. B. suis are gram-negative, facultative intracellular coccobacilli and can specifically produce in phagocytic cells. They are also non-spore-forming, non-capsulated, and non-motile. Brucella suis are differentiated into five strains. Strains 1-3 infect boars and pigs. Strain 2 has been found in wild boars but without signs of infection while they do infect pigs and hares. Brucella abortus is a species of the genus Brucella. Natural hosts of B. abortus are cattle and other bovidae. Abortion and placentitis are common effects on the pregnant animal.

When humans come in contact with an infected animal or animal products that are contaminated with Brucella, brucellosis may result. Most human infections are occupational. Over 70 percent of reported cases of brucellosis occur in the meat-processing and livestock industries. Infection is generally via skin wounds, but the organisms can also be inhaled. A common route of Brucella infection is eating or drinking infected dairy products that have not been pasteurized. Human infections are caused most frequently by B. melitensis, B. suis, and B. abortus, while B. canis causes only rare infections. B. melitensis is the most virulent. People infected with B. melitensis can suffer serious complications, including infection and inflammation of the bones and joints, and occasionally, the heart and brain. About 100-200 cases of brucellosis occur every year in the United States. Incubation period is one to three weeks, and flu like symptoms appear in the infected person, such as fever, sweats, headache, back pain, and weakness. Severe complications such as CNS infections or infections in the heart lining occur in about 5 percent of cases. Chronic symptoms like recurrent fever, arthritis, and fatigue may occur up to one year from illness onset. Information from ARUP laboratories.

Brucellosis plays an important role in the economy and health of many developing countries because of its impact on both livestock and humans. Source: Regenstrief LOINC

LP20003-7   Brucella
A genus of gram-negative, aerobic bacteria that causes BRUCELLOSIS. Its cells are nonmotile coccobacilli and are animal parasites and pathogens. The bacterium is transmissible to humans through contact with infected dairy products or tissue. Source: National Library of Medicine, MeSH 2006

Fully-Specified Name

Component
Brucella sp Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Aggl.plate.buffered acidified

Additional Names

Short Name
Brucella Ab Ser Ql Buff plate aggl
Display Name
Brucella sp Ab Acidified buffered plate agglutination Ql (S)

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.61
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Groups

LG41634-3 Brucella

Language Variants Get Info

zh-CNChinese (CHINA)
布鲁氏菌属 抗体:存在情况或阈值:时间点:血清:序数型:凝集试验法.平板.酸化缓冲
nl-NLDutch (NETHERLANDS)
Brucella sp As:aanwezigheid:moment:serum:ordinaal:agglutinatie.zuur-gebufferde plaat
fr-BEFrench (BELGIUM)
Brucella sp Ac:PrThr:Temps ponctuel:Sérum:Ordinal:Agglutination sur plaque avec antigène acidifié tamponné
fr-CAFrench (CANADA)
Brucella sp , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Agglutination sur plaque avec antigène acidifié tamponné
fr-FRFrench (FRANCE)
Brucella Ac:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Agglutination sur plaque tampon acidifié
it-ITItalian (ITALY)
Brucella sp , Ab:PrThr:Pt:Siero:Ord:Aggl.placca.tamponata acidificata
es-ESSpanish (SPAIN)
Brucella sp Anticuerpos:PrThr:Punto temporal:Suero:Ord:Aglutinación en placa tamponada con acido
tr-TRTurkish (TURKEY)
Brucella sp Ab:MevcEşik:Zmlı:Ser:Srl:Aglüt.plak.tamponlamış asitlenmiş

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=86455-3