LOINC
Version 2.72

87816-56-Monoacetylmorphine (6-MAM) [Presence] in Saliva (oral fluid) by Screen methodActive

Part Descriptions

LP14980-4   6-Monoacetylmorphine
6-Monoacetylmorphine (6-MAM) Is an intermediate metabolite between heroin and morphine. It is the primary molecule involved in the effects of heroin in the body. Heroin can cause feelings of euphoria and drowsiness. It can also lead to suicidal thoughts, liver failure, heart failure and death. Since heroin is an illicit drug, heroin and its metabolites are routinely ordered as part of a drug screen or drug abuse panel. [PMID:24595354] Source: Regenstrief LOINC

LP7565-7   Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin.[PMID:17268583] Source: Regenstrief LOINC

LP262420-5   Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual.[PMID:17268583] Source: Regenstrief LOINC

Fully-Specified Name

Component
6-Monoacetylmorphine
Property
PrThr
Time
Pt
System
Saliva
Scale
Ord
Method
Screen

Additional Names

Short Name
6MAM Sal Ql Scn
Display Name
6-Monoacetylmorphine (6-MAM) Screen Ql (Sal)
Consumer Name Alpha
6-Monoacetylmorphine (6-MAM), Saliva

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.63
Last Updated
Version 2.63
Order vs. Observation
Both

Member of these Groups

LG37549-9 6-Monoacetylmorphine|ANYProp|ANYTm|ANYSys|ANYMeth

Language Variants Get Info

zh-CNChinese (China)
6-单乙酰吗啡:存在情况或阈值:时间点:唾液:序数型:毒理学筛查试验
nl-NLDutch (Netherlands)
6-monoacetylmorfine:aanwezigheid:moment:speeksel:ordinaal:screening
fr-BEFrench (Belgium)
6-monoacétylmorphine:PrThr:Temps ponctuel:Salivaire:Ordinal:Dépistage
fr-CAFrench (Canada)
6-monoacétylmorphine:Présence-Seuil:Temps ponctuel:Salivaire:Ordinal:Dépistage
fr-FRFrench (France)
6-monoacétylmorphine:Présence/Seuil:Ponctuel:Salive:Qualitatif:Dépistage
it-ITItalian (Italy)
6-Monoacetilmorfina:PrThr:Pt:Saliva:Ord:Screening
ru-RURussian (Russian Federation)
6-моноацетилморфин:PrThr:ТчкВрм:Слюна:Пор:Скрининг
es-MXSpanish (Mexico)
6-monoacetilmorfina:Presencia o umbral:Punto temporal:Saliva:Ordinal:Pantalla de toxicología
es-ESSpanish (Spain)
6-Monoacetilmorfina:PrThr:Punto temporal:Saliva:Ord:Cribado toxicológico
tr-TRTurkish (Turkey)
6-Monoasetilmorfin:MevcEşik:Zmlı:Tükürük:Srl:Tarama

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=87816-5