LOINC
Version 2.71

88215-9Rabies virus RNA [Presence] in Saliva (oral fluid) by NAA with probe detectionActive

Part Descriptions

LP16737-6   Rabies virus
Rabies virus (RV), is an enveloped, single-stranded, negative sense RNA virus and a member of the Rhabdoviridae family. It is transmitted when an animal infected with RV bites an individual or the saliva from an infected animal comes into contact with an open wound. Once RV penetrates the muscle or connective tissue it begins to replicate and then infiltrates the peripheral nerves through the neuromuscular junction. From there, RV spreads to the central nervous system (CNS) in the endoneurium of the Schwann cells. If bitten by an animal that may have RV infection, rabies immune globulin and rabies vaccine should be administered. Otherwise, there is no treatment for infection by RV other than supportive care, and acute infection of the CNS is almost always fatal. In countries where preventative care is not practiced, RV is still widespread. In Asia, 30,000 people die annually from RV infection. Diagnosis of RV is done on two tissue specimens from the brain that are analyzed by direct fluorescent antibody (DFA), mouse inoculation, tissue culture and polymerase chain reaction.[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307483/] Source: Regenstrief LOINC

LP7565-7   Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. [PMID: 17268583] Source: Regenstrief LOINC

Fully-Specified Name

Component
Rabies virus RNA
Property
PrThr
Time
Pt
System
Saliva
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
RABV RNA Sal Ql NAA+probe
Display Name
Rabies virus RNA NAA+probe Ql (Sal)
Consumer Name Alpha
Rabies virus, Saliva

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.63
Last Updated
Version 2.63
Order vs. Observation
Both

Member of these Groups

LG32755-7 Rabies virus

Language Variants Get Info

zh-CNChinese (China)
狂犬病病毒 RNA:存在情况或阈值:时间点:唾液:序数型:探针法.基因扩增.靶向
nl-NLDutch (Netherlands)
rabiësvirus RNA:aanwezigheid:moment:speeksel:ordinaal:moleculaire techniek (PCR)
fr-BEFrench (Belgium)
Virus de la rage ARN:PrThr:Temps ponctuel:Salivaire:Ordinal:Sonde avec amplification de la cible
fr-CAFrench (Canada)
Virus de la rage , ARN:Présence-Seuil:Temps ponctuel:Salivaire:Ordinal:Sonde avec amplification de la cible
fr-FRFrench (France)
Rage virus ARN:Présence/Seuil:Ponctuel:Salive:Qualitatif:PCR amplification de cible
de-DEGerman (Germany)
Rabiesvirus RNA:NWSW:Pkt:Speichel:Ord:Probe.amp.tar
it-ITItalian (Italy)
Rabbia, virus RNA:PrThr:Pt:Saliva:Ord:Sonda.amp.tar
ru-RURussian (Russian Federation)
Бешенства вирус РНК:PrThr:ТчкВрм:Слюна:Пор:Проба.усил.миш
es-ESSpanish (Spain)
Virus de la Rabia RNA:PrThr:Punto temporal:Saliva:Ord:Sonda con amplificación dirigida
tr-TRTurkish (Turkey)
Kuduz virüsü RNA:MevcEşik:Zmlı:Tükürük:Srl:Prob.amf.hdf

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=88215-9